ArticleHernia : the journal of hernias and abdominal wall surgery2020
Comparative study of collagen and elastin content of abdominal wall fascia in inguinal hernia and non-hernia patients in an African population.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06787924 (Effect of Collagen Supplements on Dermal Collagen Content Within Skin Biopsies of Plastic Surgery and Metabolic Bariatric Surgery Patients), which is not on this map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Collagen Supplements on Dermal Collagen Content Within Skin Biopsies of Plastic Surgery and Metabolic Bariatric Surgery Patients
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- The Anatomy of the Human Linea Alba: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Genetic correlations among diaphragmatic, femoral, inguinal, ventral, and umbilical hernias and identification of their candidate genes.International journal of surgery (London, England) · 2026Article
- Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia.International journal of molecular sciences · 2025Article
- Phenotypic findings associated with variation in elastin.HGG advances · 2025Article
- Relationship Between Gestational Diabetes Mellitus and Postpartum Diastasis Recti Abdominis in Women in the First Year Postdelivery.Physical therapy · 2023Article
- Diastasis recti in the Beninese population: Cross-sectional study from normal values to diagnosis.The South African journal of physiotherapy · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAltered composition of collagen and elastin in abdominal fascia has been linked with the pathogenesis of hernias. This has not been studied amongst Africans who have hernia presentations which vary significantly from Caucasian cohorts. The aim of this study was to determine, and compare, the collagen and elastin contents of the transversalis fascia and rectus sheath of inguinal hernia patients with non-hernia controls.
methodsTwenty-five patients with solitary, primary, uncomplicated inguinal hernia and twenty-five non-hernia controls were evaluated. Biopsies of the transversalis fascia and anterior rectus sheath were stained with Masson Trichrome and Verhöeff van-Gieson to isolate collagen and elastin respectively, which were quantified using the ImageJ/Fiji® image analysis software.
resultsInguinal hernia patients were aged 19-85 years with a mean age of 45.2 years, mean body mass index (BMI) of 23.3 kg/m
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