Evidence map›Paper›PMID 32488476›Full record

ArticleSurgery today2020

Pelvic exenteration associated with future renal dysfunction.

Masanori Sando, Kay Uehara, Yuanying Li, Toshisada Aiba, Atsushi Ogura, Tomoki Ebata, Yasuhiro Kodera, Hiroshi Yatsuya, Masato Nagino

Abstract read
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In one paragraph

Article in Surgery today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Masanori SandoDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
Kay UeharaDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan. kuehara@med.nagoya-u.ac.jp.
Yuanying LiDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Toshisada AibaDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
Atsushi OguraDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
Tomoki EbataDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
Yasuhiro KoderaDepartment of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hiroshi YatsuyaDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Masato NaginoDivision of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPFujita Health University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to clarify the long-term change in the renal function after pelvic exenteration (PE) and to evaluate the risk factors for any future dysfunction.

methodsThis study comprised 40 patients. A greater than 25% decline in the estimated glomerular filtration rate (eGFR) at 3 years was defined as early renal function disorder (ERFD), possibly predicting future chronic kidney disease (CKD).

resultsIn the entire cohort, the median eGFR decreased by 23% at 3 years, and CKD developed in 50%. The patients were divided into the ERFD (n = 16) and non-ERFD (n = 24) groups. In the ERFD group, the eGFR significantly decreased by 28% during the first 1.5 years and continued to decline after that, resulting in 81.3% of patients reaching CKD, whereas it was 4% and 37.5%, respectively, in the non-ERFD group. In a growth model analysis, late urinary tract complications (UTC) and small bowel obstruction were shown to be risk factors for ERFD.

conclusionAlthough PE was associated with a high incidence of future CKD, ERFD could predict it. Close observation of the eGFR decline over 1.5 years might be beneficial to identify ERFD patients. High-risk patients with late UTC and small bowel obstruction should, therefore, be observed carefully.

Indexed as

AdultAgedBiomarkersCohort StudiesFemaleFollow-Up StudiesGlomerular Filtration RateHumansMaleMiddle AgedPelvic ExenterationPredictive Value of TestsRenal Insufficiency, ChronicRisk FactorsTime FactorsYoung AdultBiomarkersChronic kidney diseasePelvic exenterationRenal dysfunction

Identifiers

PMID32488476
OpenAlexW3032089575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.