ArticleMikrochimica acta2020
Glutathione-capped CuO nanoparticles for the determination of cystine using resonance Rayleigh scattering spectroscopy.
Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 28 citations in OpenAlex.
- Ultrafiltration Membranes Functionalized with Copper Oxide and Zwitterions for Fouling Resistance.Membranes · 2022Article
- Engineering Spherically Super-Structured Polyamides for the Sustainable Water Remediation.ACS materials Au · 2022Article
- Enhancement of Congo Red-Neomycin Resonance Rayleigh Scattering by Dodecyl Trimethyl Ammonium Bromide and its Application.International journal of analytical chemistry · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ascorbic acid was used to reduce cystine to cysteine that induces the aggregation of glutathione-capped copper oxide nanoparticles. The aggregation of CuO NPs was optimized through resonance Rayleigh scattering and dynamic light scattering measurements. The high specificity toward cysteine from other amino acids and biomolecules was due to its mercapto group that binds to the surface of CuO NPs and the electrostatic interaction between the cysteine zwitterions on the surface of CuO NPs. Accordingly, glutathione-capped copper oxide nanoparticles was used as a sensing probe for cystine based on resonance Rayleigh scattering (RRS) technique. Increase in the RRS signal of CuO NPs was observed with increasing cystine concentration. A linear calibration plot was obtained in the range 2-20 μM with a limit of detection of 4.55 ± 0.5 nM, which is lower than literature value. The applicability of the proposed sensing strategy toward cystine was established, and the recovery percentage was between 99.8 ± 0.4 and 101.0 ± 2.1 for n = 3. Graphical Abstract .
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