Evidence map›Paper›PMID 32488313›Full record

ArticleApplied microbiology and biotechnology2020

Rapid detection of antibiotic resistance genes in lactic acid bacteria using PMMA-based microreactor arrays.

Zengjun Jin, Guotao Ding, Guoxing Yang, Guiying Li, Wei Zhang, Lixin Yang, Weihao Li

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zengjun JinSchool of Medicine, Hebei University of Engineering, Handan, 056000, Hebei Province, China.
Guotao DingHandan Municipal Centre for Disease Control and Prevention, Handan, 056000, Hebei Province, China.
Guoxing YangHandan Municipal Centre for Disease Control and Prevention, Handan, 056000, Hebei Province, China.
Guiying LiSchool of Medicine, Hebei University of Engineering, Handan, 056000, Hebei Province, China.
Wei ZhangCollege of Life Sciences, Hebei Agricultural University, Baoding, 071001, China.
Lixin YangHebei Centre for Disease Control and Prevention, Shijiazhuang, 050021, Hebei Province, China.
Weihao LiHandan Municipal Centre for Disease Control and Prevention, Handan, 056000, Hebei Province, China. hdlwh@alumni.tongji.edu.cn.ORCID https://orcid.org/0000-0002-6465-7269
Hebei University of Engineering · CNHandan College · CNHebei Agricultural University · CNHebei Provincial Center for Disease Control and Prevention · CN

Funding

Hebei Province Science and Technology Support Program 17275505D
6 · The paper itself

Abstract

The emergence of lactic acid bacteria (LABs) resistant to existing antimicrobial drugs is a growing health crisis. To decrease the overuse of antibiotics, molecular diagnostic systems that can rapidly determine the presence of antibiotic resistance (AR) genes in LABs from yogurt samples are needed. This paper describes a fully integrated, miniaturized plastic chip and closed-tube detection chemistry that performs multiplex nucleic acid amplification. High-throughput identification of AR genes was achieved through this approach, and six AR genes were analyzed simultaneously in < 2 h. This time-to-result included the time required for the extraction of DNA. The detection limit of the chip was 10

Indexed as

Genes, BacterialAnti-Bacterial AgentsDrug Resistance, BacterialFood MicrobiologyLactobacillalesMicrobial Sensitivity TestsMicrofluidicsNucleic Acid Amplification TechniquesPolymethyl MethacrylateSensitivity and SpecificityYogurtAnti-Bacterial AgentsPolymethyl MethacrylateAntibiotic resistance genesLactic acid bacteriaLAMPMicrofluidicsMicroreactor arrays

Identifiers

PMID32488313
OpenAlexW3030143827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.