Evidence map›Paper›PMID 32488230›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2020

Gray Matter Structure Is Associated with Reading Skill in Typically Developing Young Readers.

Meaghan V Perdue, Joshua Mednick, Kenneth R Pugh, Nicole Landi

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Heritable and experience-dependent cortical traits of reading ability.Cerebral cortex (New York, N.Y. : 1991) · 2026
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  15. Neuroimaging genetic associations betweenJournal of clinical and experimental neuropsychology · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meaghan V PerdueUniversity of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Joshua MednickUniversity of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Kenneth R PughUniversity of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Nicole LandiUniversity of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
THE FLORIDA LONGITUDINAL STUDYP50HD052120 · NICHD · FLORIDA STATE UNIVERSITY · PI CHRIS W SCHATSCHNEIDER · 2006 to 2026
$31.7M
Visual word identification: phonology &morphologyP01HD001994 · NICHD · HASKINS LABORATORIES, INC. · PI ZEVIN, JASON D · 1985 to 2016
$23.5M
Tracking neurocognitive changes during evidence-based reading instruction in typically and atypically developing childrenR37HD090153 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI Kenneth R. Pugh · 2017 to 2026
$6.0M
Experiential and child factors that determine acquisition of orthographic-phonological regularities in a quasi-regular writing system: An integrated behavioral/computational/neurobiological approachP20HD091013 · NICHD · FLORIDA STATE UNIVERSITY · PI COMPTON, DONALD L · 2017 to 2025
$4.2M
Neurochemistry as a moderator of brain networks for readingR01HD086168 · NICHD · HASKINS LABORATORIES, INC. · PI HOEFT, FUMIKO, PUGH, KENNETH R. · 2016 to 2020
$3.2M
Neurobiological Foundations of reading (dis)abilityR01HD048830 · NICHD · YALE UNIVERSITY · PI PUGH, KENNETH R. · 2005 to 2010
$3.0M
Neurobiology of language function in adolescents exposed to cocaine in uteroR21DA030665 · NIDA · YALE UNIVERSITY · PI MAYES, LINDA CAROL · 2011 to 2012
$410k
Neurocognitive development in RD children with/without general cognitive deficitsR03HD053409 · NICHD · HASKINS LABORATORIES, INC. · PI LANDI, NICOLE · 2008 to 2009
$141k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS P01 HD001994NICHD NIH HHS P20 HD091013NICHD NIH HHS P50 HD052120NICHD NIH HHS R01 HD048830NICHD NIH HHS R01 HD086168NICHD NIH HHS R03 HD053409NICHD NIH HHS R37 HD090153NIDA NIH HHS R21 DA030665
6 · The paper itself

Abstract

Research using functional and structural magnetic resonance imaging has identified areas of reduced brain activation and gray matter volume in children and adults with reading disability, but associations between cortical structure and individual differences in reading in typically developing children remain underexplored. Furthermore, the majority of research linking gray matter structure to reading ability quantifies gray matter in terms of volume, and cannot specify unique contributions of cortical surface area and thickness to these relationships. Here, we applied a continuous analytic approach to investigate associations between distinct surface-based properties of cortical structure and individual differences in reading-related skills in a sample of typically developing young children. Correlations between cortical structure and reading-related skills were conducted using a surface-based vertex-wise approach. Cortical thickness in the left superior temporal cortex was positively correlated with word and pseudoword reading performance. The observed positive correlation between cortical thickness in the left superior temporal cortex and reading may have implications for the patterns of brain activation that support reading.

Indexed as

ReadingBrainChildChild DevelopmentChild, PreschoolFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMalechildrencortical surface areacortical thicknessindividual differencesneuroimagingreading

Identifiers

PMID32488230
PMCPMC7566659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.