Evidence map›Paper›PMID 32488206›Full record

ArticleInternational journal of impotence research2021

Comparing the Italian and North American prospective registries on penile prosthesis surgery: are there relevant differences in treatment indications and patients' management?

Federico Deho', Gerard Henry, Edward Karpman, Edoardo Pescatori, Fulvio Colombo, Carlo Bettocchi, Giovanni Liguori, Carlo Ceruti, Nicola Mondaini, Stefano Fiordelise and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International journal of impotence research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 20 institutions in 2 countries.

Federico Deho'Ospedale San Raffaele, Vita-Salute University, Milano, Italy. deho.federico@gmail.com.
Gerard HenryArkLaTex Urology, Bossier City, LA, USA.
Edward KarpmanEl Camino Urology Medical Group, Inc, Mountain View, CA, USA.
Edoardo PescatoriHesperia Hospital, Modena, Italy.
Fulvio ColomboPoliclinico S.Orsola-Malpighi, Bologna, Italy.
Carlo BettocchiPoliclinico Bari, Bari, Italy.
Giovanni LiguoriOspedali Riuniti, Trieste, Italy.ORCID http://orcid.org/0000-0003-2431-5296
Carlo CerutiClinica Urologica della Città della Salute e della Scienza, Torino, Italy.
Nicola MondainiNuovo San Giovanni di Dio Hospital, Florence, Italy.
Stefano FiordeliseUOS Andrologia ASL, Piacenza, Italy.
Alessandro PalmieriUniversità Federico II, Napoli, Italy.
Paolo CapogrossoOspedale San Raffaele, Vita-Salute University, Milano, Italy.
INSIST-ED study group
Azienda Ospedaliero Universitaria Ospedali Riuniti · ITPoliclinico Umberto I · ITAzienda Sanitaria Locale di Asti · ITAmerican University of Rome · ITIRCCS Ospedale San Raffaele · ITL'organizzazione Ospedale di Civitanova M · ITOspedale Antonio Cardarelli · ITOspedale degli Infermi · ITOspedale Santa Chiara · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera Ospedale San Carlo Borromeo · ITAzienda Unità Sanitaria Locale Piacenza · ITEl Camino Urology Medical Group · USFondazione Ricerca Molinette · ITHesperia Hospital · ITInternational Centre for Advanced Mediterranean Agronomic Studies · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITNuovo Ospedale San Giovanni di Dio · ITOspedale L. Bonomo · ITOspedale Maggiore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown discrepancies among countries in terms of treatment indications and patients' management due to different health care policies. Penile prosthesis implantation (PPI) is a highly effective treatment for erectile dysfunction (ED), which may have different accessibility according to the type of health system. We compared clinical characteristics of patients included in two national registries on PPI to investigate the influence of different health care systems on treatment indication and accessibility. The multicenter Italian Nationwide Systematic Inventarization of Surgical Treatment for ED (INSIST-ED) Registry and the multicenter Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration (PROPPER), respectively for Italy and North America were considered. Clinical characteristics of patients included in both registries were compared using Wilcoxon Rank Sum test and the Pearson's Chi square test. Patients submitted to PPI in Italy are significantly younger (age: 61.2 vs. 63.8 years; p ≤ 0.001) compared with North America. The majority of patients are treated for post-radical prostatectomy ED in both registries (Italy: 31%; North America: 27%), although diabetes and cardiovascular diseases are more frequent reasons for PPI in the PROPPER registry (p ≤ 0.001), reflecting differences in disease prevalence among countries. In North America a non-hydraulic implant is considered only in 1% of cases as compared with 3% in Italy (p ≤ 0.001). In terms of postoperative management, a compressive surgical dressing (98% vs. 24%; p ≤ 0.001) is a more common strategy in North America. Finally, in Italy most surgeries are performed in a public hospital (82%), while the private setting (70.8%) is more common in North America (p ≤ 0.001). These findings suggest differences in health care systems between Italy and North America. A system like the American one would guarantee easier access to PPI in countries where the National Health System is mainly based on reimbursement to public hospital settings and where patients choosing private settings have to pay by themselves.

Indexed as

Penile ImplantationPenile ProsthesisHumansItalyMaleMiddle AgedNorth AmericaRegistries

Identifiers

PMID32488206
OpenAlexW3032175464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.