ArticleTranslational psychiatry2020
Neural responsivity to social rewards in autistic female youth.
Article in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Distinct neurobiological alterations during hedonic experience of rewards in attention deficit hyperactivity disorder and autism spectrum disorder: Multimodal evidence from neuroimaging meta-analyses.Molecular psychiatry · 2026Pooled it
- Sex/gender differences in the human autistic brains: A systematic review of 20 years of neuroimaging research.NeuroImage. Clinical · 2021Pooled it
- Brain-based sex differences in autism spectrum disorder across the lifespan: A systematic review of structural MRI, fMRI, and DTI findings.NeuroImage. Clinical · 2021Pooled it
- Modeling how autistic and non-autistic groups learn about their own and each other's preferences.Nature. Mental health · 2026Article
- Functional Connectivity During Social Reward Processing in Autistic and Neurotypical Adolescents.Brain and behavior · 2026Article
- Reward processing differences in autism: current understandings and future directions.Social cognitive and affective neuroscience · 2026Review
- Neural signals gradually shift towards inferior frontal gyrus and long-term effects following facial imitation-based social learning.NPJ science of learning · 2025Article
- Linking Subclinical Autistic Traits and Perceptual Category Learning.The European journal of neuroscience · 2025Article
- Microalgae-based bacteria for oral treatment of ASD through enhanced intestinal colonization and homeostasis.Theranostics · 2025Article
- Spontaneous instrumental approach-avoidance learning in social contexts in autism.Molecular autism · 2024Article
- Differently different?: A commentary on the emerging social cognitive neuroscience of female autism.Biology of sex differences · 2024Review
- Social intuition: behavioral and neurobiological considerations.Frontiers in psychology · 2024Article
- Social motivation by self- and caregiver-report: Reporter concordance and social correlates among autistic and neurotypical youth.Autism research : official journal of the International Society for Autism Research · 2024Article
- Investigating Sex-Based Neural Differences in Autism and Their Extended Reality Intervention Implications.Brain sciences · 2023Review
- Role of Artificial Intelligence for Autism Diagnosis Using DTI and fMRI: A Survey.Biomedicines · 2023Article
- Sex differences in externalizing and internalizing traits and ventral striatal responses to monetary loss.Journal of psychiatric research · 2023Article
- The autism spectrum among transgender youth: default mode functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Social-interactive reward elicits similar neural response in autism and typical development and predicts future social experiences.Developmental cognitive neuroscience · 2023Article
- Comparative analysis of group information-guided independent component analysis and independent vector analysis for assessing brain functional network characteristics in autism spectrum disorder.Frontiers in neuroscience · 2023Article
- Ties between reading faces, bodies, eyes, and autistic traits.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
16 authors at 9 institutions in 1 country.
Funding
Abstract
Autism is hypothesized to be in part driven by a reduced sensitivity to the inherently rewarding nature of social stimuli. Previous neuroimaging studies have indicated that autistic males do indeed display reduced neural activity to social rewards, but it is unknown whether this finding extends to autistic females, particularly as behavioral evidence suggests that affected females may not exhibit the same reduction in social motivation as their male peers. We therefore used functional magnetic resonance imaging to examine social reward processing during an instrumental implicit learning task in 154 children and adolescents (ages 8-17): 39 autistic girls, 43 autistic boys, 33 typically developing girls, and 39 typically developing boys. We found that autistic girls displayed increased activity to socially rewarding stimuli, including greater activity in the nucleus accumbens relative to autistic boys, as well as greater activity in lateral frontal cortices and the anterior insula compared with typically developing girls. These results demonstrate for the first time that autistic girls do not exhibit the same reduction in activity within social reward systems as autistic boys. Instead, autistic girls display increased neural activation to such stimuli in areas related to reward processing and salience detection. Our findings indicate that a reduced sensitivity to social rewards, as assessed with a rewarded instrumental implicit learning task, does not generalize to affected female youth and highlight the importance of studying potential sex differences in autism to improve our understanding of the condition and its heterogeneity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.