ArticleScientific reports2020
In vivo assessment of foveal geometry and cone photoreceptor density and spacing in children.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Use of a Retinal Phantom to Facilitate Adaptive Optics Scanning Light Ophthalmoscopy Imaging in a Multicenter Clinical Trial.Translational vision science & technology · 2026Trial
- Photopic pupil size, foveal anatomy and emmetropisation: a cross-sectional study in adult eyes.BMJ open ophthalmology · 2026Article
- Retinal and Choroidal Microvasculature at Different Myopia Severities: A Systematic Review and Meta-Analysis.Ophthalmology science · 2026Review
- In vivo assessment of cone loss and macular perfusion in children with myopia.Scientific reports · 2024Observational
- Adaptive Optics Retinal Imaging in RDH12-Associated Early Onset Severe Retinal Dystrophy.Investigative ophthalmology & visual science · 2024Article
- The effect of sampling window size on topographical maps of foveal cone density.Frontiers in ophthalmology · 2024Article
- Cone Density Is Correlated to Outer Segment Length and Retinal Thickness in the Human Foveola.Investigative ophthalmology & visual science · 2023Article
- A variation of foveal morphology in a group of children with hypermetropia.International ophthalmology · 2023Article
- IMI-Nonpathological Human Ocular Tissue Changes With Axial Myopia.Investigative ophthalmology & visual science · 2023Article
- Macular outer nuclear layer, ellipsoid zone and outer photoreceptor segment band thickness, axial length and other determinants.Scientific reports · 2023Article
- Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited].Biomedical optics express · 2023Review
- Photoreceptor density in relation to axial length and retinal location in human eyes.Scientific reports · 2022Article
- Retinal magnification factors at the fixation locus derived from schematic eyes with four individualized surfaces.Biomedical optics express · 2022Article
- Longitudinal In Vivo Changes in Radial Peripapillary Capillaries and Optic Nerve Head Structure in Non-Human Primates With Early Experimental Glaucoma.Investigative ophthalmology & visual science · 2022Article
- Quantification of macular perfusion in healthy children using optical coherence tomography angiography.International journal of retina and vitreous · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The fovea undergoes significant developmental changes from birth into adolescence. However, there is limited data examining cone photoreceptor density, foveal pit shape, and foveal avascular zone (FAZ) size in children. The purpose of this study was to determine whether overall foveal structure differs as a function of age and refractive status in children. Forty-eight healthy children (ages 5.8 to 15.8 years) underwent optical coherence tomography imaging to quantify foveal point thickness and foveal pit diameter, depth, and slope. Adaptive optics scanning laser ophthalmoscope (AOSLO) images of foveal capillaries and cone photoreceptors were acquired in a subset of children to quantify FAZ metrics and cone densities at 0.2, 0.3, and 0.5 mm eccentricities. Results show that foveal pit and FAZ metrics were not related to age, axial length, or refractive status. However, linear cone density was lower in myopic versus non-myopic children at eccentricities of 0.2 mm (mean ± SD = 50,022 ± 5,878 cones/mm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.