Evidence map›Paper›PMID 32487917›Full record

ReviewAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Translational Retinal Imaging.

Jorge Orellana-Rios, Sho Yokoyama, Alauddin Bhuiyan, Liang Gao, Oscar Otero-Marquez, R Theodore Smith

Open access · diamondAbstract readReview
In one paragraph

Review in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Advances and Latest Developments in Ophthalmology and Visual Sciences.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Jorge Orellana-RiosFundación Oftalmológica Los Andes, Vitacura, Santiago de Chile, Chile.
Sho YokoyamaDepartment of Ophthalmology, Japan Community Healthcare Organization, Chukyo Hospital, Nagoya, Aichi, Japan.
Alauddin BhuiyaniHealthScreen Inc, New York, NY, USA.
Liang GaoDepartment of Biomedical Engineering, UCLA, LA, Los Angeles, CA, USA.
Oscar Otero-MarquezDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
R Theodore SmithDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USChukyo Hospital · JPEcoHealth Alliance · USFundación Chile · CLUniversity of California, Los Angeles · US

Funding

Validated Autofluorescence in Age-Related Macular DegenerationR01EY015520 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SMITH, ROLAND THEODORE · 2005 to 2018
$6.0M
Hyperspectral Imaging of the Normal and Age-related Macular Degeneration FundusR01EY021470 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FAWZI, AMANI A, SMITH, ROLAND THEODORE · 2011 to 2014
$3.4M
NEI NIH HHS R01 EY015520NEI NIH HHS R01 EY021470
6 · The paper itself

Abstract

The diagnosis and treatment of medical retinal disease is now inseparable from retinal imaging in all its multimodal incarnations. The purpose of this article is to present a selection of very different retinal imaging techniques that are truly translational, in the sense that they are not only new, but can guide us to new understandings of disease processes or interventions that are not accessible by present methods. Quantitative autofluorescence imaging, now available for clinical investigation, has already fundamentally changed our understanding of the role of lipofuscin in age-related macular degeneration. Hyperspectral autofluorescence imaging is bench science poised not only to unravel the molecular basis of retinal pigment epithelium fluorescence, but also to be translated into a clinical camera for earliest detection of age-related macular degeneration. The ophthalmic endoscope for vitreous surgery is a radically new retinal imaging system that enables surgical approaches heretofore impossible while it captures subretinal images of living tissue. Remote retinal imaging coupled with deep learning artificial intelligence will transform the very fabric of future medical care.

Indexed as

Artificial IntelligenceFluorescein AngiographyFundus OculiHumansMacular DegenerationOphthalmoscopyRetinal Pigment EpitheliumTomography, Optical Coherence

Identifiers

PMID32487917
PMCPMC7299229
OpenAlexW3029727652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.