ArticleEpidemiology (Cambridge, Mass.)2020
Changes in Behavior with Increasing Pregnancy Attempt Time: A Prospective Cohort Study.
Article in Epidemiology (Cambridge, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Female dietary patterns and outcomes of in vitro fertilization (IVF): a systematic literature review.Nutrition journal · 2022Pooled it
- The Role of Maternal Preconception Adiposity in Human Offspring Sex and Sex Ratio.American journal of epidemiology · 2023Trial
- A Preconception Cohort Study of Nicotine Vaping and Incidence of Spontaneous Abortion.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- A preconception cohort study of historical mortgage lending discrimination and present-day fecundability.American journal of epidemiology · 2026Article
- Racialized economic segregation in relation to fecundability in a preconception cohort study.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- A prospective study of semen quality and fecundability among North American couples planning pregnancy.Andrology · 2026Article
- Preconception alcohol consumption in both partners and risk of miscarriage.Reproductive biomedicine online · 2025Article
- A prospective study of male physical activity and fecundability.Human reproduction (Oxford, England) · 2025Article
- Exposure to residential greenness, perceived stress, and depressive symptoms in a North American preconception cohort.Environmental research · 2024Article
- A preconception cohort study of sugar-sweetened beverage consumption and semen quality.Andrology · 2024Article
- The association between the use of fertility indicators and fecundability in a Danish preconception cohort.Paediatric and perinatal epidemiology · 2024Article
- Preconception sleep duration, non-daytime work schedules, and incidence of spontaneous abortion: a prospective cohort study.Human reproduction (Oxford, England) · 2024Article
- Air pollution and fecundability in a North American preconception cohort study.Environment international · 2023Article
- Associations between Residential Greenspace and Fecundability in a North American Preconception Cohort Study.Environmental health perspectives · 2023Article
- Concordance of self-reported sexual intercourse frequency between members of mixed-sex couples attempting conception.The Canadian journal of human sexuality · 2022Article
- Association Between Neighborhood Disadvantage and Fertility Among Pregnancy Planners in the US.JAMA network open · 2022Article
- Predictive models of pregnancy based on data from a preconception cohort study.Human reproduction (Oxford, England) · 2022Article
- Maternal caffeine intake and DNA methylation in newborn cord blood.The American journal of clinical nutrition · 2022Article
- Feasibility of leveraging menstrual cycle tracking apps for preconception research recruitment.Frontiers in reproductive health · 2022Article
- Antibiotics and fecundability among female pregnancy planners: a prospective cohort study.Human reproduction (Oxford, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe extent to which couples change their behaviors with increasing pregnancy attempt time is not well documented.
methodsWe examined change in selected behaviors over pregnancy attempt time in a North American preconception cohort study. Eligible females were ages 21-45 years and not using fertility treatment. Participants completed baseline and bimonthly follow-up questionnaires for up to 12 months or until pregnancy.
resultsAmong 3,339 females attempting pregnancy for 0-1 cycles at enrollment, 250 contributed 12 months of follow-up without conceiving. Comparing behaviors at 12 months versus baseline, weighted for loss-to-follow-up, we observed small-to-moderate reductions in mean caffeine intake (-19.5 mg/day, CI = -32.7, -6.37), alcohol intake (-0.85 drinks/week, CI = -1.28, -0.43), marijuana use (-3.89 percentage points, CI = -7.33, 0.46), and vigorous exercise (-0.68 hours/week, CI = -1.05, -0.31), and a large increase in activities to improve conception chances (e.g., ovulation testing) (21.7 percentage points, CI = 14.8, 28.6). There was little change in mean cigarette smoking (-0.27 percentage points, CI = -1.58, 1.04), perceived stress scale score (-0.04 units, CI = -0.77, 0.69), or other factors (e.g., sugar-sweetened soda intake, moderate exercise, intercourse frequency, and multivitamin use), but some heterogeneity within subgroups (e.g., 31% increased and 32% decreased their perceived stress scores by ≥2 units; 14% reduced their smoking but none increased their smoking by ≥5 cigarettes/day).
conclusionsAlthough many behaviors changed with increasing pregnancy attempt time, mean changes tended to be modest for most variables. The largest differences were observed for the use of caffeine, alcohol, and marijuana, and methods to improve conception chances.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.