Evidence map›Paper›PMID 32487766›Full record

ArticleJournal of neurointerventional surgery2021

Lower complication rates associated with transradial versus transfemoral flow diverting stent placement.

Yangchun Li, Stephanie H Chen, Alejandro M Spiotta, Pascal Jabbour, Michael R Levitt, Peter Kan, Christoph J Griessenauer, Adam S Arthur, Joshua W Osbun, Min S Park and 35 more

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Comparative safety, efficacy, and predictors of complete occlusion of flow diverter devices in the treatment of unruptured distal anterior cerebral artery aneurysms.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors at 17 institutions in 2 countries.

Yangchun Li *Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.ORCID http://orcid.org/0000-0002-3634-883X
Stephanie H Chen *Department of Neurological Surgery, University of Miami School of Medicine, Miami, Florida, USA.
Alejandro M SpiottaNeurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Pascal JabbourNeurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0002-1544-4910
Michael R LevittNeurological Surgery, Radiology and Mechanical Engineering and Stroke and Applied Neuroscience Center, University of Washington, Seattle, Washington, USA.
Peter KanDepartment of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Christoph J GriessenauerNeurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.
Adam S ArthurDepartment of Neurological Surgery, Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee, USA.ORCID http://orcid.org/0000-0002-1536-1613
Joshua W OsbunNeurosurgery, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA.
Min S ParkNeurological Surgery, University of Virginia, Charlottesville, Virginia, USA.
Nohra ChalouhiNeurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Ahmad SweidNeurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Stacey Q WolfeNeurosurgery, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.
Kyle M FargenNeurosurgery, Wake Forest University, Winston-Salem, North Carolina, USA.
Aaron S DumontDepartment of Neurological Surgery, Tulane University, New Orleans, Louisiana, USA.
Travis M DumontNeurosurgery, Neurology and Medical Imaging, University of Arizona/Arizona Health Science Center, Tucson, Arizona, USA.
Marie-Christine BrunetDepartment of Neurological Surgery, University of Miami School of Medicine, Miami, Florida, USA.
Samir SurNeurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Evan LutherDepartment of Neurological Surgery, University of Miami School of Medicine, Miami, Florida, USA.ORCID http://orcid.org/0000-0001-9164-4984
Allison StricklandDepartment of Neurological Surgery, University of Miami School of Medicine, Miami, Florida, USA.
Dileep R YavagalNeurology and Neurosurgery, University of Miami, Miami, Florida, USA.
Eric C PetersonNeurological Surgery, University of Miami, Miami, Florida, USA.
Clemens M SchirmerNeurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.
Oded GorenNeurosurgery, Geisinger, Danville, Pennsylvania, USA.
Shamsher DalalNeurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.
Gregory WeinerNeurosurgery, Geisinger Health System, Wilkes-Barre, Pennsylvania, USA.
Axel RosengartNeurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.
Daniel RaperDepartment of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID http://orcid.org/0000-0003-3378-5345
Ching-Jen ChenNeurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.
Peter AmentaNeurological Surgery, Tulane Medical Center Downtown, New Orleans, Louisiana, USA.
Tyler ScullenNeurosurggery, Tulane University, New Orleans, Louisiana, USA.
Cory Michael KellyNeurological Surgery, University of Washington, Seattle, Washington, USA.
Christopher YoungNeurological Surgery, University of Washington, Seattle, Washington, USA.ORCID http://orcid.org/0000-0002-3679-3212
Michael NahhasNeurology, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID http://orcid.org/0000-0001-8198-7676
Eyad AlmallouhiNeurology, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID http://orcid.org/0000-0002-6873-7901
Arunprasad GunasekaranNeurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Suhas PaiNeurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Giuseppe LanzinoNeurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
Waleed BrinjikjiNeurosurgery, Mayo Clinic Minnesota, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0001-5271-5524
Mehdi AbbasiNeurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
David Dornbos IiiNeurosurgery, Semmes-Murphey Clinic, Memphis, Tennessee, USA.
Nitin GoyalNeurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jeremy PetersonNeurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Mohammad H El-GhanemNeurosurgery, Neurology and Medical Imaging, University of Arizona Health Sciences Center, Tucson, Arizona, USA.
Robert M StarkeNeurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA RStarke@med.miami.edu.
University of Miami · USMedical University of South Carolina · USUniversity of Tennessee Health Science Center · USGeisinger Health System · USMayo Clinic · USThomas Jefferson University Hospital · USUniversity of Washington · USNeurological Surgery · USParacelsus Medical University · ATTulane University · USUniversity of Arizona · USWake Forest University · USBaylor College of Medicine · USGeisinger Medical Center · USTulane Medical Center · USUniversity of Virginia Health System · USWashington University in St. Louis · US

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
Improving the computational modeling of coiled cerebral aneurysms through synchrotron microtomographyR01NS105692 · NINDS · UNIVERSITY OF WASHINGTON · PI Michael Robert Levitt · 2018 to 2026
$3.5M
Endothelial cell dysfunction in cerebral aneurysm pathogenesisR01NS111119 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI STARKE, ROBERT MICHAEL · 2020 to 2024
$2.4M
University of Washington HUB Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN)U24NS100654 · NINDS · UNIVERSITY OF WASHINGTON · PI Nicholas J Johnson, Peter James Kudenchuk · 2017 to 2026
$2.1M
Predicting cerebral aneurysm recurrence using Doppler guidewire measurementsR01NS088072 · NINDS · UNIVERSITY OF WASHINGTON · PI KIM, LOUIS JOONG · 2014 to 2018
$1.7M
NCATS NIH HHS KL2 TR002737NCATS NIH HHS UL1 TR002736NINDS NIH HHS R01 NS088072NINDS NIH HHS R01 NS105692NINDS NIH HHS R01 NS111119NINDS NIH HHS U24 NS100654
6 · The paper itself

Abstract

backgroundCurrently, there are no large-scale studies in the neurointerventional literature comparing safety between transradial (TRA) and transfemoral (TFA) approaches for flow diversion procedures. This study aims to assess complication rates in a large multicenter registry for TRA versus TFA flow diversion.

methodsWe retrospectively analyzed flow diversion cases for cerebral aneurysms from 14 institutions from 2010 to 2019. Pooled analysis of proportions was calculated using weighted analysis with 95% CI to account for results from multiple centers. Access site complication rate and overall complication rate were compared between the two approaches.

resultsA total of 2,285 patients who underwent flow diversion were analyzed, with 134 (5.86%) treated with TRA and 2151 (94.14%) via TFA. The two groups shared similar patient and aneurysm characteristics. Crossover from TRA to TFA was documented in 12 (8.63%) patients. There were no access site complications in the TRA group. There was a significantly higher access site complication rate in the TFA cohort as compared with TRA (2.48%, 95% CI 2.40% to 2.57%, vs 0%; p=0.039). One death resulted from a femoral access site complication. The overall complications rate was also higher in the TFA group (9.02%, 95% CI 8.15% to 9.89%) compared with the TRA group (3.73%, 95% CI 3.13% to 4.28%; p=0.035).

conclusionTRA may be a safer approach for flow diversion to treat cerebral aneurysms at a wide range of locations. Both access site complication rate and overall complication rate were lower for TRA flow diversion compared with TFA in this large series.

Indexed as

Postoperative ComplicationsAdultAgedCatheterization, PeripheralCohort StudiesEndovascular ProceduresFemaleFemoral ArteryHumansIntracranial AneurysmMaleMiddle AgedRadial ArteryRegistriesRetrospective StudiesSelf Expandable Metallic Stentsaneurysmarterycomplicationflow diverterintervention

Identifiers

PMID32487766
PMCPMC7708402
OpenAlexW3030869022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.