Evidence map›Paper›PMID 32487759›Full record

ArticlemBio2020

Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca

Martin Weichert, José Guirao-Abad, Vishukumar Aimanianda, Karthik Krishnan, Christina Grisham, Patrick Snyder, Alex Sheehan, Ruthvik R Abbu, Hong Liu, Scott G Filler and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  9. Fungi of the order Mucorales express a "sealing-only" tRNA ligase.bioRxiv : the preprint server for biology · 2023
    Article
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  12. TheMicrobiology spectrum · 2022
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  13. Cell death induction inCurrent research in microbial sciences · 2022
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Martin Weichert *Department of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
José Guirao-Abad *Department of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Vishukumar AimaniandaInstitut Pasteur, Molecular Mycology Unit, CNRS, UMR2000, Paris, France.ORCID 0000-0001-5813-7497
Karthik KrishnanDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Christina GrishamDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Patrick SnyderDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Alex SheehanDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Ruthvik R AbbuDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Hong LiuDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Scott G FillerDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0001-7278-3700
Eric I GruensteinDepartment of Molecular Genetics, Biochemistry & Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Jean-Paul LatgéUnité des Aspergillus, Institut Pasteur, Paris, France.
David S AskewDepartment of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA david.askew@uc.edu.
University of Cincinnati Medical Center · USUCLA Medical Center · USCentre National de la Recherche Scientifique · FRInstitut Pasteur · FR

Funding

ER stress and calcium in host adaptation of A. fumigatusR01AI123158 · NIAID · UNIVERSITY OF CINCINNATI · PI ASKEW, DAVID S · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI123158
6 · The paper itself

Abstract

Many species of pathogenic fungi deploy the unfolded protein response (UPR) to expand the folding capacity of the endoplasmic reticulum (ER) in proportion to the demand for virulence-related proteins that traffic through the secretory pathway. Although Ca

Indexed as

Endoplasmic Reticulum StressUnfolded Protein ResponseA549 CellsAdenosine TriphosphatasesAlveolar Epithelial CellsAnimalsAspergillus fumigatusCalciumCell WallEndoplasmic ReticulumFemaleFungal ProteinsGolgi ApparatusHumansMaleMiceAdenosine TriphosphatasesCalciumFungal ProteinsAspergillus fumigatuscalciumcell wallER stressgalactomannanHacASERCASPCAUPR

Identifiers

PMID32487759
PMCPMC7267887
OpenAlexW3029935175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.