Evidence map›Paper›PMID 32487756›Full record

ArticlemBio2020

NOD1/NOD2 and RIP2 Regulate Endoplasmic Reticulum Stress-Induced Inflammation during

Oanh H Pham, Bokyung Lee, Jasmine Labuda, A Marijke Keestra-Gounder, Mariana X Byndloss, Renée M Tsolis, Stephen J McSorley

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Infection and immunity · 2026
    Article
  4. Resolving the field: a role for Nod2 in T cells.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Oanh H Pham *Center for Immunology and Infectious Diseases, Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.
Bokyung Lee *Center for Immunology and Infectious Diseases, Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.
Jasmine LabudaCenter for Immunology and Infectious Diseases, Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.
A Marijke Keestra-GounderDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, USA.ORCID 0000-0002-2231-652X
Mariana X ByndlossDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, USA.ORCID 0000-0002-2122-4156
Renée M TsolisDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, USA.ORCID 0000-0001-9131-6657
Stephen J McSorleyCenter for Immunology and Infectious Diseases, Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA sjmcsorley@ucdavis.edu.
University of California, Davis · US

Funding

Salmonella-specific Th1 cell function and residenceR01AI139047 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2019 to 2023
$1.9M
CD4 T cell responses to Chlamydia infectionR01AI103422 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2016 to 2019
$1.5M
Generation of a TCR transgenic mouse to study Chlamydia genital tract infectionR21AI117303 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2015 to 2016
$422k
NIAID NIH HHS R01 AI103422NIAID NIH HHS R01 AI139047NIAID NIH HHS R21 AI117303
6 · The paper itself

Abstract

The inflammatory response to

Indexed as

Immunity, InnateAnimalsBacterial LoadChlamydia InfectionsChlamydia muridarumEndoplasmic Reticulum StressInflammationMiceMice, Inbred C57BLNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor ProteinReceptor-Interacting Protein Serine-Threonine Kinase 2Signal TransductionSpecific Pathogen-Free OrganismsNod1 protein, mouseNod1 Signaling Adaptor ProteinNod2 protein, mouseNod2 Signaling Adaptor ProteinReceptor-Interacting Protein Serine-Threonine Kinase 2Ripk2 protein, mouseChlamydiaER stressinflammationinnate immunityNOD

Identifiers

PMID32487756
PMCPMC7267884
OpenAlexW3031957991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.