Evidence map›Paper›PMID 32487750›Full record

ArticleThe Journal of biological chemistry2020

Spontaneous and photosensitization-induced mutations in primary mouse cells transitioning through senescence and immortalization.

Andrew W Caliri, Stella Tommasi, Steven E Bates, Ahmad Besaratinia

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew W CaliriDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Stella TommasiDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Steven E BatesDepartment of Cancer Biology, Beckman Research Institute of the City of Hope, Duarte, California, USA.
Ahmad BesaratiniaDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, USA besarati@med.usc.edu.ORCID 0000-0001-7231-228X
University of Southern California · USCity of Hope · US

Funding

Genetic epigenetic & transcripotomic effects of e-cig aerosol on oral epitheliumR01DE026043 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BESARATINIA, AHMAD · 2016 to 2019
$1.6M
NCIRD CDC HHS R01 IP000051NIDCR NIH HHS R01 DE026043
6 · The paper itself

Abstract

To investigate the role of oxidative stress-induced DNA damage and mutagenesis in cellular senescence and immortalization, here we profiled spontaneous and methylene blue plus light-induced mutations in the

Indexed as

MutagenesisMutation8-Hydroxy-2'-DeoxyguanosineAnimalsCells, CulturedCellular SenescenceHumansMiceMice, Transgenic8-Hydroxy-2'-Deoxyguanosine8-oxoguanine (8-oxoG)cancerDNA damageDNA mismatch repairimmortalizationmouse embryonic fibroblasts (MEF)mutagenesisoncogenesisoxidative stressphotodynamic therapyreactive oxygen species (ROS)senescencetransversion

Identifiers

PMID32487750
PMCPMC7380187
OpenAlexW3030317475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.