Evidence map›Paper›PMID 32487195›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2020

33% hydrogen peroxide as a Neoadjuvant treatment in the surgical excision of non-melanoma skin cancers: a case series.

N Mundi, K Jordan, P Doyle, C Moore

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Phytochemical Characterization ofAntioxidants (Basel, Switzerland) · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

N MundiDepartment of Otolaryngology - Head and Neck Surgery, London Health Sciences Centre, Victoria Hospital, University of Western Ontario, 800 Commissioners Road E, London, ON, N6A 5W9, Canada. neilmundi@gmail.com.ORCID http://orcid.org/0000-0001-9328-8266
K JordanDepartments of Oncology and Biophysics, University of Western Ontario, London, Ontario, Canada.
P DoyleDepartment of Otolaryngology - Head and Neck Surgery, London Health Sciences Centre, Victoria Hospital, University of Western Ontario, 800 Commissioners Road E, London, ON, N6A 5W9, Canada.
C MooreDepartment of Otolaryngology - Head and Neck Surgery, London Health Sciences Centre, Victoria Hospital, University of Western Ontario, 800 Commissioners Road E, London, ON, N6A 5W9, Canada.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHydrogen peroxide (H

methodsEleven consecutive patients presenting to our cutaneous malignancy clinic had their skin lesions evaluated by the senior author for participation in the study. Lesion length and width was measured. Hydrogen peroxide formulated at a concentration of 33% was rubbed into the lesion until blanching was observed. Lesions were re-measured at follow up. Excisional biopsy was then performed and histopathological diagnosis was obtained. Statistical analyses compared pre- and post-treatment lesion dimensions.

resultsSeventeen biopsy-proven NMSC lesions were included in this investigation. Statistically significant reductions in the length (p < 0.001) and width (p < 0.001) were observed with H

conclusionsWe have demonstrated a significant reduction in the size of multiple lesions after application of 33% hydrogen peroxide, simplifying definitive excision and reconstruction. Hydrogen peroxide demonstrated an ability to successfully treat non-melanoma skin cancers as well.

Indexed as

Administration, CutaneousAgedAged, 80 and overBasal Cell CarcinomaBiopsyCarcinoma, Squamous CellFemaleHumansHydrogen PeroxideMaleMargins of ExcisionMiddle AgedNeoadjuvant TherapySkin NeoplasmsHydrogen PeroxidePeroxideSkin neoplasms

Identifiers

PMID32487195
PMCPMC7268291
OpenAlexW3032620327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.