Evidence map›Paper›PMID 32486903›Full record

ArticlePharmacogenomics2020

Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.

Vera Kim, Thijs van der Wal, Miriam Yumie Nishi, Luciana Ribeiro Montenegro, Flair Jose Carrilho, Yujin Hoshida, Suzane Kioko Ono

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05515653 (Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05515653 unknown statusnot on this mapstarted 2022, after this paper: background citation

Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population

TypeobservationalSponsorHospital Alemão Oswaldo CruzRan2022 to 2024Enrolled3,974ConditionsCardiovascular Diseases, Acute MI, Stroke, Peripheral Arterial DiseaseArmsExposure to genetics (polygenic)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Vera KimDivision of Clinical Gastroenterology & Hepatology, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.ORCID 0000-0003-0840-0247
Thijs van der WalDivision of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Miriam Yumie NishiUnidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.
Luciana Ribeiro MontenegroUnidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.
Flair Jose CarrilhoDivision of Clinical Gastroenterology & Hepatology, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.
Yujin HoshidaDivision of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Suzane Kioko OnoDivision of Clinical Gastroenterology & Hepatology, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.
Universidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRIcahn School of Medicine at Mount Sinai · USThe University of Texas Southwestern Medical Center · US

Funding

Reverse-engineering precision liver cancer chemopreventionR01CA233794 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HOSHIDA, YUJIN · 2019 to 2023
$3.5M
Molecular Prognostic Indicators in Liver Cirrhosis and CancerR01DK099558 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOSHIDA, YUJIN · 2013 to 2016
$2.6M
NCI NIH HHS R01 CA233794NIDDK NIH HHS R01 DK099558
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBrazilCohort StudiesFemaleHumansMaleMembrane Transport ProteinsMiddle AgedPharmaceutical PreparationsPharmacogeneticsPharmacokineticsPolymorphism, Single NucleotideMembrane Transport ProteinsPharmaceutical PreparationsADME genesadmixture populationBraziliangenetic diversitynext-generation sequencingpharmacogenomics

Identifiers

PMID32486903
PMCPMC7362932
OpenAlexW3030261262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.