Evidence map›Paper›PMID 32486849›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2020

Yi-Sheng Xiao, Hua-Zhang Tong, Xi-Hong Yuan, Chang-Hui Xiong, Xiao-Yang Xu, Yuan-Feng Zeng

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  3. Journal of gastrointestinal oncology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Sheng XiaoTeaching and Researching Section of Morphology, College of Traditional Chinese Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Hua-Zhang TongDepartment of Oncology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006, China.
Xi-Hong YuanDepartment of General Surgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006, China.
Chang-Hui XiongDepartment of Science and Education, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006, China.
Xiao-Yang XuDepartment of General Surgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006, China.
Yuan-Feng ZengDepartment of Pathology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006, China.ORCID 0000-0003-4174-3575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementColorectal cancer (CRC) is the third most common malignancy worldwide with the second highest mortality rate. Although multidisciplinary cooperative therapies are helpful for improving the survival of CRC patients, the prognosis remains poor. Therefore, it is imperative to seek new biomarkers for the development of individualized treatment for each CRC patient. Circular RNA, an endogenous transcript with specific covalent closed loop, exhibits higher stability, conservation and expression abundance than the corresponding linear component and thus may be utilized as a promised biomarker. Although the majority of studies have focused on circular RNA expression profiling in various types of cancers, evidence supporting their critical role in the diagnosis and prognosis of CRC is limited. This study aimed to screen and identify novel circular RNA biomarkers of CRC by chip analysis and qPCR verification, and to highlight their potential as targets for CRC prognosis, and therapy.

Indexed as

AgedBiomarkers, TumorCell DifferentiationColorectal NeoplasmsFatty Acid DesaturasesFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingPrognosisProportional Hazards ModelsRNA, CircularBiomarkers, TumorFADS2 protein, humanFatty Acid DesaturasesRNA, Circularbiomarkerscancer progressioncircFADS2colorectal cancerprognosis

Identifiers

PMID32486849
PMCPMC7437371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.