ArticleCirculation2020
Temporal Trends in Prevalence and Prognostic Implications of Comorbidities Among Patients With Acute Decompensated Heart Failure: The ARIC Study Community Surveillance.
Article in Circulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Prevalence of Pulmonary Hypertension in Individuals With Heart Failure: A Systematic Review and Meta-Analysis.Clinical cardiology · 2025Pooled it
- Combined endurance and resistance exercise training in heart failure with preserved ejection fraction: a randomized controlled trial.Nature medicine · 2025Trial
- Peak OESC heart failure · 2022Trial
- Comparison of outcomes after ablation of atrial fibrillation in patients with heart failure with preserved versus reduced ejection fraction: a US retrospective cohort analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Impact of routine urine sodium evaluation on diuretic practices in patients with acute heart failure.ESC heart failure · 2026Article
- Circulating pro-angiogenic cells are preserved despite myocardial angiogenic signal deficits in HFpEF model.Scientific reports · 2026Article
- Non-Cardiac Comorbidities in Acute Heart Failure: Phenotype-Specific Insights from Sub-Saharan Africa.Journal of clinical medicine · 2026Article
- Heart failure with preserved ejection fraction: a systemic condition of comorbidities.Heart failure reviews · 2026Review
- The association between polypharmacy and mortality in patients with heart failure: Results from the PULSE dataset.ESC heart failure · 2025Observational
- Comorbidity patterns and mortality in HFpEF: A retrospective longitudinal cohort study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Comorbidity Disease Pattern in Japanese Elderly Population: A Network-Based Analysis.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Outpatient heart failure specialist care following acute heart failure hospitalisation improves long-term outcomes.Open heart · 2025Article
- Article
- Temporal trends in incidence, clinical characteristics and outcomes among young adults with heart failure: a territory-wide study from 2014 to 2023 on 19,537 patients.The Lancet regional health. Western Pacific · 2025Article
- A Comprehensive Profile of Heart Failure Patients Across Ejection Fraction Subtypes: Insights from a Single-Center Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- Cardiovascular-kidney-metabolic overlaps, clinical outcomes, and quality of life in patients with acute heart failure.The journal of nutrition, health & aging · 2025Article
- Eight-Year Survival Analysis of Patients With Dilated Cardiomyopathy: Does Treatment Era Affect Prognosis?Cureus · 2025Article
- Inter-atrial block as a predictor of adverse outcomes in patients with HFpEF.ESC heart failure · 2025Article
- Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos.Circulation research · 2025Review
- Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.Circulation · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatients with heart failure (HF) have multiple coexisting comorbidities. The temporal trends in the burden of comorbidities and associated risk of mortality among patients with HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF) are not well established.
methodsHF-related hospitalizations were sampled by stratified design from 4 US areas in 2005 to 2014 by the community surveillance component of the ARIC study (Atherosclerosis Risk in Communities). Acute decompensated HF was classified by standardized physician review and a previously validated algorithm. An ejection fraction <50% was considered HFrEF. A total of 15 comorbidities were abstracted from the medical record. Mortality outcomes were ascertained for up to 1-year postadmission by linking hospital records with death files.
resultsA total of 5460 hospitalizations (24 937 weighted hospitalizations) classified as acute decompensated HF had available ejection fraction data (53% female, 68% white, 53% HFrEF, 47% HFpEF). The average number of comorbidities was higher for patients with HFpEF versus HFrEF, both for women (5.53 versus 4.94;
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