Evidence map›Paper›PMID 32486511›Full record

ArticleInternational journal of molecular sciences2020

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone.

Viktor A Timoshnikov, Tatyana V Kobzeva, Nikolay E Polyakov, George J Kontoghiorghes

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 152 citations in OpenAlex.

  1. Pooled it
  2. Enzymatic and non-enzymatic oxidation of fibrillar collagen.Redox report : communications in free radical research · 2026
    Review
  3. Review
  4. Article
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  7. Review
  8. Review
  9. Review
  10. Iron-ascorbate complex formation and redox behavior in Tris buffer under aerobic and anaerobic conditions: relevance to iron-deficiency anemia.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  11. Review
  12. Review
  13. Potential Antidote Against Lead Toxicity-A Review.International journal of molecular sciences · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Viktor A TimoshnikovInstitute of Chemical Kinetics & Combustion, Novosibirsk zip code: 630090, Russia.
Tatyana V KobzevaInstitute of Chemical Kinetics & Combustion, Novosibirsk zip code: 630090, Russia.
Nikolay E PolyakovInstitute of Chemical Kinetics & Combustion, Novosibirsk zip code: 630090, Russia.ORCID 0000-0002-3666-7750
George J KontoghiorghesPostgraduate Research Institute of Science, Technology, Environment and Medicine, CY-3504 Limassol, Cyprus.ORCID 0000-0002-3364-7340
Institute of Chemical Kinetics and Combustion · RUResearch Institute of Health Sciences · ES

Funding

Ministry of Education and Science of the Russian Federation 0304-2017-0009Российский Фонд Фундаментальных Исследований (РФФИ) 18-34-00343
6 · The paper itself

Abstract

Ascorbic acid (AscH

Indexed as

Ascorbic AcidChelating AgentsDeferiproneElectron Spin Resonance SpectroscopyHydrogen-Ion ConcentrationHydrogen PeroxideHydroxyl RadicalIronIron Chelating AgentsMagnetic Resonance SpectroscopyOxidantsOxidation-ReductionOxygenReactive Oxygen SpeciesSpectrophotometry, UltravioletAscorbic AcidChelating AgentsDeferiproneFenton's reagentHydrogen PeroxideHydroxyl RadicalIronIron Chelating AgentsOxidantsOxygenReactive Oxygen Speciesascorbic acidascorbyl radicaldeferiproneEPR spin trappingFenton reactionhydroxyl radicaliron chelationiron toxicityTMIO spin trapvitamin C

Identifiers

PMID32486511
PMCPMC7312906
OpenAlexW3031116360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.