Evidence map›Paper›PMID 32486426›Full record

ArticleCancers2020

Functional Characterization of POFUT1 Variants Associated with Colorectal Cancer.

Marlène Deschuyter, Florian Pennarubia, Emilie Pinault, Sébastien Legardinier, Abderrahman Maftah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. ProteinMolecules (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Significant Roles of NotchMolecules (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Marlène DeschuyterPEIRENE, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges, F-87060 Limoges, France.
Florian PennarubiaPEIRENE, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges, F-87060 Limoges, France.
Emilie PinaultPEIRENE, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges, F-87060 Limoges, France.ORCID 0000-0001-8811-2661
Sébastien LegardinierPEIRENE, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges, F-87060 Limoges, France.ORCID 0000-0001-5923-5689
Abderrahman MaftahPEIRENE, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges, F-87060 Limoges, France.ORCID 0000-0002-0196-435X
Université de Limoges · FRCentre National de la Recherche Scientifique · FRUniversity of Georgia · US

Funding

Ligue Contre le Cancer Maftah 2018
6 · The paper itself

Abstract

backgroundProtein

methodsRecombinant secreted forms of human WT POFUT1 and its seven mutated counterparts were produced and purified. Their

findingsMS analyses showed a significantly higher

interpretationThis study provides insights on the possible involvement of these seven missense mutations in colorectal tumors. The hyperactive forms could lead to an increased

Indexed as

colorectal cancerEGF-like domainmutationsPOFUT1

Identifiers

PMID32486426
PMCPMC7352195
OpenAlexW3030528190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.