Evidence map›Paper›PMID 32486408›Full record

ReviewMolecules (Basel, Switzerland)2020

Combretastatins: An Overview of Structure, Probable Mechanisms of Action and Potential Applications.

Gökçe Şeker Karatoprak, Esra Küpeli Akkol, Yasin Genç, Hilal Bardakci, Çiğdem Yücel, Eduardo Sobarzo-Sánchez

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Cytotoxic Activity of Chemical Constituents ofPlants (Basel, Switzerland) · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Synthesis and Biological Evaluation of NewMolecules (Basel, Switzerland) · 2025
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gökçe Şeker KaratoprakDepartment of Pharmacognosy, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey.
Esra Küpeli AkkolDepartment of Pharmacognosy Faculty of Pharmacy, Gazi University, 06330 Ankara, Turkey.
Yasin GençDepartment of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Sıhhiye, Ankara, Turkey.
Hilal BardakciDepartment of Pharmacognosy, Faculty of Pharmacy, Acibadem Mehmet Ali Aydınlar University, 34752 Istanbul, Turkey.
Çiğdem YücelDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey.
Eduardo Sobarzo-SánchezInstituto de Investigación e Innovación en Salud, Facultad de Ciencias de la Salud, Universidad Central de Chile, 8330507 Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combretastatins are a class of closely related stilbenes (combretastatins A), dihydrostilbenes (combretastatins B), phenanthrenes (combretastatins C) and macrocyclic lactones (combretastatins D) found in the bark of

Indexed as

AnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsAntiparasitic AgentsCaco-2 CellsCell Line, TumorCell ProliferationCombretumDrug Delivery SystemsHT29 CellsHumansMelanoma, ExperimentalSolubilityStereoisomerismAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsAntiparasitic Agentscombretastatin B-1fosbretabulinStilbenesTubulinTubulin ModulatorsWatercombretaceaecombretastatinsdrug discoverynanoformulationnatural compoundstructure-activity relationshipstubulin inhibitors.

Identifiers

PMID32486408
PMCPMC7321081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.