Evidence map›Paper›PMID 32486318›Full record

ArticleGenes2020

Association of Common Genetic Variants in the

Ignazio S Piras, Christiane Bleul, Ashley Siniard, Amanda J Wolfe, Matthew D De Both, Alvaro G Hernandez, Matthew J Huentelman

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Best practices for analyzing imputed genotypes from low-pass sequencing in dogs.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ignazio S PirasNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Christiane BleulNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Ashley SiniardNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Amanda J WolfeNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Matthew D De BothNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Alvaro G HernandezRoy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Matthew J HuentelmanNeurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.ORCID 0000-0001-7390-9918
Translational Genomics Research Institute · USUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine idiopathic pulmonary fibrosis (CIPF) is a chronic fibrotic lung disease that is observed at a higher frequency in the West Highland White Terrier dog breed (WHWT) and may have molecular pathological overlap with human lung fibrotic disease. We conducted a genome-wide association study (GWAS) in the WHWT using whole genome sequencing (WGS) to discover genetic variants associated with CIPF. Saliva-derived DNA samples were sequenced using the Riptide DNA library prep kit. After quality controls, 28 affected, 44 unaffected, and 1,843,695 informative single nucleotide polymorphisms (SNPs) were included in the GWAS. Data were analyzed both at the single SNP and gene levels using the

Indexed as

Genetic Association StudiesAnimalsDog DiseasesDogsGenetic Predisposition to DiseaseHumansIdiopathic Pulmonary FibrosisMitochondrial ProteinsPolyadenylationPolymorphism, Single NucleotideRNA Recognition Motif ProteinsCPSF7 protein, humanMitochondrial ProteinsRNA Recognition Motif ProteinsSDHAF2 protein, humananimal geneticsgenomicspulmonary fibrosis

Identifiers

PMID32486318
PMCPMC7349241
OpenAlexW3030453080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.