The Structural Basis of the Binding of Various Aminopolycarboxylates by the Periplasmic EDTA-Binding Protein EppA from

Kevin M Lewis, Chelsie L Greene, Steven A Sattler, Buhyun Youn, Luying Xun, ChulHee Kang

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 48% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Sensory Perception in Bacterial Cyclic Diguanylate Signal Transduction.Journal of bacteriology · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Kevin M LewisDepartment of Chemistry, Washington State University, Pullman, WA 99163, USA.ORCID 0000-0003-3403-9520

Chelsie L GreeneDepartment of Chemistry, Washington State University, Pullman, WA 99163, USA.

Steven A SattlerSchool of Molecular Biosciences, Washington State University, Pullman, WA 99163, USA.

Buhyun YounDepartment of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea.

Luying XunSchool of Molecular Biosciences, Washington State University, Pullman, WA 99163, USA.ORCID 0000-0002-5770-9016

ChulHee KangDepartment of Chemistry, Washington State University, Pullman, WA 99163, USA.ORCID 0000-0002-0693-7860

Washington State University · USPusan National University · KR

Funding

National Science Foundation CHE 1804699

6 · The paper itself

Abstract

The widespread use of synthetic aminopolycarboxylates, such as ethylenediaminetetraacetate (EDTA), as chelating agents has led to their contamination in the environment as stable metal-chelate complexes. Microorganisms can transport free EDTA, but not metal-EDTA complexes, into cells for metabolism. An ABC-type transporter for free EDTA uptake in

Indexed as

ATP-Binding Cassette TransportersBacterial ProteinsCalorimetryCarboxylic AcidsChelating AgentsCrystallography, X-RayEdetic AcidLigandsLightMolecular Docking SimulationMutagenesis, Site-DirectedPeriplasmic Binding ProteinsPhyllobacteriaceaeProtein BindingProtein ConformationProtein DomainsATP-Binding Cassette TransportersBacterial ProteinsCarboxylic AcidsChelating AgentsEdetic AcidLigandsPeriplasmic Binding ProteinsABC transportbioremediationcrystal structureEDTAisothermal titration calorimetryperiplasmic binding protein

Identifiers

PMID32486296

DOI10.3390/ijms21113940

PMCPMC7312458

OpenAlexW3029572791

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.