Evidence map›Paper›PMID 32486275›Full record

ArticleBiomedicines2020

Higher Epoxyeicosatrienoic Acids in Cardiomyocytes-Specific CYP2J2 Transgenic Mice Are Associated with Improved Myocardial Remodeling.

Theresa Aliwarga, Xiaoyun Guo, Eric A Evangelista, Rozenn N Lemaitre, Nona Sotoodehnia, Sina A Gharib, Darryl C Zeldin, Qinghang Liu, Rheem A Totah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Theresa AliwargaDepartment of Medicinal Chemistry, University of Washington, Box 357610, Seattle, WA 98195, USA.
Xiaoyun GuoDepartment of Physiology and Biophysics, University of Washington, Box 357290, Seattle, WA 98195, USA.
Eric A EvangelistaDepartment of Medicinal Chemistry, University of Washington, Box 357610, Seattle, WA 98195, USA.
Rozenn N LemaitreCardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA.
Nona SotoodehniaCardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA.
Sina A GharibComputational Medicinal Core, Center for Lung Biology, Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, S376-815 Mercer, Box 385052, Seattle, WA 98109, USA.
Darryl C ZeldinNational Institute of Environmental Health Sciences, A214 Rall Building, 111 T W Alexander Dr, Research Triangle Park, NC 27709, USA.
Qinghang LiuDepartment of Physiology and Biophysics, University of Washington, Box 357290, Seattle, WA 98195, USA.
Rheem A TotahDepartment of Medicinal Chemistry, University of Washington, Box 357610, Seattle, WA 98195, USA.
University of Washington · USNational Institute of Environmental Health Sciences · US

Funding

Characterization And Functional Significance Of P450 Arachidonate EpoxygenasesZIAES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$18.6M
CYP2J2 Mediated Eicosanoids in Arrhythmias and Sudden Cardiac ArrestR01HL128709 · NHLBI · UNIVERSITY OF WASHINGTON · PI SOTOODEHNIA, NONA, TOTAH, RHEEM ANGELA · 2015 to 2018
$2.9M
Epoxyeicosatrienoic acids, diabetes, and cardiovascular diseaseR01HL130880 · NHLBI · UNIVERSITY OF WASHINGTON · PI LEMAITRE, ROZENN, TOTAH, RHEEM ANGELA · 2016 to 2019
$2.8M
NHLBI NIH HHS R01 HL128709NHLBI NIH HHS R01 HL130880NIH HHS R01HL130880, R01HL088456 and R01HL096706
6 · The paper itself

Abstract

Elevated

Indexed as

CYP2J2epoxyeicosatrienoic acidsmyocardial remodeling

Identifiers

PMID32486275
PMCPMC7344501
OpenAlexW3029184094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.