Evidence map›Paper›PMID 32486261›Full record

ArticleInternational journal of molecular sciences2020

Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization.

Preeti Kumari Chaudhary, Sanggu Kim, Youngheun Jee, Seung-Hun Lee, Kyung-Mee Park, Soochong Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Targeting platelet-tumor cell interactions: a novel approach to cancer therapy.Medical oncology (Northwood, London, England) · 2025
    Review
  3. Article
  4. Article
  5. The GRKs Reactome: Role in Cell Biology and Pathology.International journal of molecular sciences · 2021
    Review
  6. The Roles of GRKs in Hemostasis and Thrombosis.International journal of molecular sciences · 2020
    Review
  7. Article
  8. C1-inhibitor influence on platelet activation by thrombin receptors agonists.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Preeti Kumari ChaudharyCollege of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Sanggu KimCollege of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Youngheun JeeCollege of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 63243, Korea.
Seung-Hun LeeCollege of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Kyung-Mee ParkCollege of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Soochong KimCollege of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Chungbuk National University · KR

Funding

National Research Foundation of Korea NRF-2016R1D1A1B01010310
6 · The paper itself

Abstract

Platelet G protein-coupled receptors (GPCRs) regulate platelet function by mediating the response to various agonists, including adenosine diphosphate (ADP), thromboxane A

Indexed as

Gene Expression RegulationPlatelet Activation15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAdenosine DiphosphateAnimalsBlood PlateletsFemaleG-Protein-Coupled Receptor KinasesHemostaticsMaleMiceMice, KnockoutOligopeptidesPhosphorylationPlatelet AggregationReceptors, G-Protein-Coupled15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAdenosine Diphosphatealanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanineG-protein-coupled receptor kinase 6G-Protein-Coupled Receptor KinasesHemostaticsmethylthio-ADPOligopeptidesReceptors, G-Protein-CoupledThionucleotidesThrombinThromboxane A2ADPdesensitizationGPCRGRK6PARplatelets

Identifiers

PMID32486261
PMCPMC7312169
OpenAlexW3031228642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.