Evidence map›Paper›PMID 32486252›Full record

ArticleInternational journal of molecular sciences2020

Hypersensitivity of Airway Reflexes Induced by Hydrogen Sulfide: Role of TRPA1 Receptors.

Chi-Li Chung, You Shuei Lin, Nai-Ju Chan, Yueh-Yin Chen, Chun-Chun Hsu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chi-Li ChungSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-0656-976X
You Shuei LinDepartment of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Nai-Ju ChanGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Yueh-Yin ChenGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chun-Chun HsuSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-2319-2151

Funding

Ministry of Education DP2-108-21121-01-T-01-03Ministry of Science and Technology, Taiwan MOST108-2320-B-038-059-MY3, MOST103-2320-B-038-014 and MOST104-2320-B-038-029Taipei Medical University Hospital 105TMU-TMUH-12
6 · The paper itself

Abstract

The activation of capsaicin-sensitive lung vagal (CSLV) afferents can elicit airway reflexes. Hypersensitivity of these afferents is known to contribute to the airway hypersensitivity during airway inflammation. Hydrogen sulfide (H

Indexed as

AcetanilidesAdministration, InhalationAerosolsAnimalsCalciumCapsaicinCoughGuinea PigsHeart RateHydrogen SulfideInfusions, IntraventricularLungMaleNeuronsPurinesRats2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamideAcetanilidesAerosolsCalciumCapsaicinHydrogen SulfidePurinessodium bisulfideSulfidesTRPA1 Cation Channelairway inflammationairway reflexC-fibersH2Ssensory neuronTRPA1

Identifiers

PMID32486252
PMCPMC7312894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.