Evidence map›Paper›PMID 32486192›Full record

ArticleBiomolecules2020

Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties.

Raluca Bianca Tomoiagă, Souad Diana Tork, Ilka Horváth, Alina Filip, Levente Csaba Nagy, László Csaba Bencze

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raluca Bianca TomoiagăBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.
Souad Diana TorkBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.
Ilka HorváthBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.
Alina FilipBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.
Levente Csaba NagyBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.ORCID 0000-0002-6356-6349
László Csaba BenczeBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, Arany János street 11, RO-400028 Cluj-Napoca, Romania.ORCID 0000-0003-0956-9749
Babeș-Bolyai University · RO

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PROMYS_IZ11Z0_166543
6 · The paper itself

Abstract

Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted the substrate specificity-modulator role of residue I460 of

Indexed as

BiocatalysisMolecular Docking SimulationMutationPetroselinumPhenylalanine Ammonia-LyasePhenylalanine Ammonia-Lyasebiocatalysisphenylalanine ammonia-lyasesprotein engineeringsaturation mutagenesis

Identifiers

PMID32486192
PMCPMC7355458
OpenAlexW3030854455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.