Evidence map›Paper›PMID 32486089›Full record

ArticleInternational journal of molecular sciences2020

Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide.

Yosuke Hirotsu, Udo Schmidt-Edelkraut, Hiroshi Nakagomi, Ikuko Sakamoto, Markus Hartenfeller, Ram Narang, Theodoros G Soldatos, Sajo Kaduthanam, Xiaoyue Wang, Stephan Hettich and 3 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yosuke HirotsuGenome Analysis Center, Yamanashi Central Hospital, Kofu 400-8506, Japan.ORCID 0000-0002-8002-834X
Udo Schmidt-EdelkrautMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.ORCID 0000-0003-2594-609X
Hiroshi NakagomiDepartment of Breast Surgery, Yamanashi Central Hospital, Kofu 400-8506, Japan.
Ikuko SakamotoDepartment of Obstetrics and Gynecology, Yamanashi Central Hospital, Kofu 400-8506, Japan.
Markus HartenfellerMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Ram NarangMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Theodoros G SoldatosMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Sajo KaduthanamMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Xiaoyue WangMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Stephan HettichMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Stephan BrockMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
David B JacksonMolecular Health GmbH, Research Department, 69115 Heidelberg, Germany.
Masao OmataGenome Analysis Center, Yamanashi Central Hospital, Kofu 400-8506, Japan.
Yamanashi Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genes, BRCA1Genes, BRCA2Biomarkers, TumorBreast NeoplasmsComputational BiologyDNA RepairFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticGenetic Predisposition to DiseaseGenetic TestingGenetic VariationGermanyGerm-Line MutationHumansJapanBiomarkers, TumorPoly(ADP-ribose) Polymerase InhibitorsBRCA1BRCA2CancerHBOCPARP inhibition

Identifiers

PMID32486089
PMCPMC7312854
OpenAlexW3032512767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.