Evidence map›Paper›PMID 32485946›Full record

ArticleBiomedicines2020

Synthesis and In Vitro Photodynamic Activity of Cationic Boron Dipyrromethene-Based Photosensitizers against Methicillin-Resistant

Priyanga Dharmaratne, Roy C H Wong, Jun Wang, Pui-Chi Lo, Baiyan Wang, Ben C L Chan, Kit-Man Lau, Clara B S Lau, Kwok-Pui Fung, Margaret Ip and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Antimicrobial photodynamic activity of a BODIPY on an alternative preclinical model Galleria mellonella.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  4. A Bioorthogonal Antidote Against the Photosensitivity after Photodynamic Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Priyanga DharmaratneSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.ORCID 0000-0002-2084-0643
Roy C H WongDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Jun WangDepartment of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.
Pui-Chi LoDepartment of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.
Baiyan WangSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Ben C L ChanInstitute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.ORCID 0000-0001-5505-1065
Kit-Man LauInstitute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Clara B S LauInstitute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.ORCID 0000-0002-7409-1270
Kwok-Pui FungSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Margaret IpDepartment of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong.ORCID 0000-0003-1291-6537
Dennis K P NgDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.

Funding

Health and Medical Research Fund, Hong Kong (SAR) HMRF 16151202
6 · The paper itself

Abstract

A series of cationic boron dipyrromethene (BODIPY) derivatives were synthesized and characterized with various spectroscopic methods. Having the ability to generate singlet oxygen upon irradiation, these compounds could potentially serve as photosensitizers for antimicrobial photodynamic therapy. Of the five BODIPYs being examined, the dicationic aza-BODIPY analogue (compound

Indexed as

antimicrobialsboron dipyrromethenesmethicillin-resistant Staphylococcus aureusphotodynamic therapyphotosensitizers

Identifiers

PMID32485946
PMCPMC7344895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.