Evidence map›Paper›PMID 32485930›Full record

ArticleVaccines2020

Protective Efficacy of a Chimeric Insect-Specific Flavivirus Vaccine against West Nile Virus.

Laura J Vet, Yin Xiang Setoh, Alberto A Amarilla, Gervais Habarugira, Willy W Suen, Natalee D Newton, Jessica J Harrison, Jody Hobson-Peters, Roy A Hall, Helle Bielefeldt-Ohmann

Abstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura J VetSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.ORCID 0000-0001-7587-2936
Yin Xiang SetohSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.ORCID 0000-0002-1683-3555
Alberto A AmarillaSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.
Gervais HabarugiraSchool of Veterinary Science, University of Queensland Gatton Campus, Queensland 4343, Australia.ORCID 0000-0001-5858-0421
Willy W SuenSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.
Natalee D NewtonSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.ORCID 0000-0002-5617-8639
Jessica J HarrisonSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.
Jody Hobson-PetersSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.ORCID 0000-0003-0139-9829
Roy A HallSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.
Helle Bielefeldt-OhmannSchool of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia.

Funding

National Health and Medical Research Council APP1138611
6 · The paper itself

Abstract

Virulent strains of West Nile virus (WNV) are highly neuro-invasive and human infection is potentially lethal. However, no vaccine is currently available for human use. Here, we report the immunogenicity and protective efficacy of a vaccine derived from a chimeric virus, which was constructed using the structural proteins (prM and E) of the Kunjin strain of WNV (WNV

Indexed as

chimeric flavivirusinsect-specific flavivirusvaccineWest Nile virus

Identifiers

PMID32485930
PMCPMC7349994

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.