Evidence map›Paper›PMID 32485908›Full record

ArticleViruses2020

Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes.

Lise Lauterbach-Rivière, Maïwenn Bergez, Saskia Mönch, Bingqian Qu, Maximilian Riess, Florian W R Vondran, Juliane Liese, Veit Hornung, Stephan Urban, Renate König

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  17. [Immune status of inactive HBsAg antigen carriers with chronic HBV infection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Lise Lauterbach-RivièreHost-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.
Maïwenn BergezHost-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.
Saskia MönchHost-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.
Bingqian QuDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Maximilian RiessHost-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.
Florian W R VondranRegenerative Medicine and Experimental Surgery (ReMediES), Department of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany.
Juliane LieseDepartment of General and Thoracic Surgery, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Veit HornungGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
Stephan UrbanDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Renate KönigHost-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.ORCID 0000-0003-4882-9179
Paul Ehrlich Institut · DEHeidelberg University · DEJustus-Liebig-Universität Gießen · DELudwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DESanford Burnham Prebys Medical Discovery Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus

Indexed as

Signal TransductionBlotting, WesternCell LineCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, ViralFluorescent Antibody TechniqueHepatitis BHepatitis B virusHepatocytesHep G2 CellsHumansImmunity, InnateMembrane ProteinsNucleotidyltransferasesSTING ProteincGAS protein, humanCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, ViralMembrane ProteinsNucleotidyltransferasesSTING1 protein, humanSTING ProteincGAShepatitis B virus (HBV)innate immune sensinginnate immunityinterferon responseSTING

Identifiers

PMID32485908
PMCPMC7354540
OpenAlexW3032475356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.