ArticleAnimals : an open access journal from MDPI2020
Size Matters: Zoo Data Analysis Shows that the White Blood Cell Ratio Differs between Large and Small Felids.
Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Xenobiotic exposure may confound traditional stress biomarkers: evaluating perfluoropentanoic acid and cadmium effects on largemouth bass (Conservation physiology · 2026Article
- Immune-cancer analyses across mammals reveal a potential trophic level and platelet-linked tradeoff between cancer and trauma mortality.bioRxiv : the preprint server for biology · 2025Article
- Laparoscopic-assisted ovariohysterectomy for pyometra with concurrent endometriosis in a captive cheetah (Open veterinary journal · 2025Article
- Determination of hematological and biochemical values blood parameters for European bison (Bison bonasus).PloS one · 2024Article
- Inbreeding Coefficient and Distance in MHC Genes of Parents as Predictors of Reproductive Success in Domestic Cat.Animals : an open access journal from MDPI · 2022Article
- Hematological and Biochemical Reference Values in Healthy Captive Tigers (Animals : an open access journal from MDPI · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The total number of white blood cells (WBCs) is related the immune system. In mammals, it is affected by the body mass, but it is unclear how the numbers of different WBC types correlate with this parameter. We analyzed the effect of body mass on WBC number and ratio in felids, where species are similar in diet (warm-blood vertebrates) and reproductive strategy (promiscuity). Based on zoo veterinary data (ZIMS database) we analyzed the effect of body mass on WBC number and neutrophils/lymphocytes ratio in 26 species of felids. The number of WBCs correlated with the body masses of animals: large cats had more WBC, which may be due to greater risks of infection associated with larger body surface, lifespan and home range size. For the first time we found obvious differences in the number of WBC types. Large cats also had more neutrophils and monocytes but fewer lymphocytes than smaller cats. The ratio of neutrophils to lymphocytes is greater in large felids. This phenomenon may be related to diet (relative prey size and kill utilization time), which suggests regular contact of large cats with bacterial and protozoal pathogens in contrast to the small cats.
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