ReviewJournal of fungi (Basel, Switzerland)2020
Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives.
Review in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Diagnostic Approaches to Invasive Candidiasis: Challenges and New Perspectives.Mycopathologia · 2025Review
- New insights into radiolabelled siderophores for molecular imaging of bacterial infections.Npj imaging · 2025Review
- Fimsbactin Siderophores From a South African Marine Sponge Symbiont, Marinomonas sp. PE14-40.Microbial biotechnology · 2025Article
- FpnA, the Aspergillus fumigatus homolog of human ferroportin, mediates resistance to nickel, cobalt and gallium but does not function in iron homeostasis.Communications biology · 2025Article
- Radiotracers for in situ infection imaging: Experimental considerations for in vitro microbial uptake of gallium-68-labeled siderophores.Diagnostic microbiology and infectious disease · 2024Article
- Biosynthesis of iron-chelating terramides A-C and their role in Aspergillus terreus infection.Communications chemistry · 2024Article
- Biomimetic Analogues of the Desferrioxamine E Siderophore for PET Imaging of Invasive Aspergillosis: Targeting Properties and Species Specificity.Journal of medicinal chemistry · 2024Article
- Preclinical characterisation of gallium-68 labeled ferrichrome siderophore stereoisomers for PET imaging applications.EJNMMI radiopharmacy and chemistry · 2024Article
- Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi.Microbial biotechnology · 2023Review
- The Siderophore Ferricrocin Mediates Iron Acquisition in Aspergillus fumigatus.Microbiology spectrum · 2023Article
- Article
- Biosynthesis Pathways, Transport Mechanisms and Biotechnological Applications of Fungal Siderophores.Journal of fungi (Basel, Switzerland) · 2021Review
- Cyclic Analogs of Desferrioxamine E Siderophore forInorganic chemistry · 2021Article
- Radionuclide Imaging of Invasive Fungal Disease in Immunocompromised Hosts.Diagnostics (Basel, Switzerland) · 2021Review
- The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores inJournal of fungi (Basel, Switzerland) · 2021Article
- Desferrioxamine B-Mediated Pre-Clinical In Vivo Imaging of Infection by the Mold FungusJournal of fungi (Basel, Switzerland) · 2021Article
- Leveraging copper import by yersiniabactin siderophore system for targeted PET imaging of bacteria.JCI insight · 2021Article
- Radionuclide Imaging of Fungal Infections and Correlation with the Host Defense Response.Journal of fungi (Basel, Switzerland) · 2021Review
- Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy ofJournal of fungi (Basel, Switzerland) · 2020Article
- Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis.Journal of fungi (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Invasive fungal infections such as aspergillosis are life-threatening diseases mainly affecting immuno-compromised patients. The diagnosis of fungal infections is difficult, lacking specificity and sensitivity. This review covers findings on the preclinical use of siderophores for the molecular imaging of infections. Siderophores are low molecular mass chelators produced by bacteria and fungi to scavenge the essential metal iron. Replacing iron in siderophores by radionuclides such as gallium-68 allowed the targeted imaging of infection by positron emission tomography (PET). The proof of principle was the imaging of pulmonary
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.