ArticlePolymers2020
Hybrid Unilamellar Vesicles of Phospholipids and Block Copolymers with Crystalline Domains.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Lipid Membrane Leaflets Unzip upon Hybridization with Polymer-Rich Nanodomains.Macromolecules · 2024Article
- Unveiling the Performance of Co-Assembled Hybrid Nanocarriers: Moving towards the Formation of a Multifunctional Lipid/Random Copolymer Nanoplatform.Pharmaceutics · 2024Article
- Advances in block copolymer-phospholipid hybrid vesicles: from physical-chemical properties to applications.Chemical science · 2024Review
- Deciphering the Lipid-Random Copolymer Interactions and Encoding Their Properties to Design a Hybrid System.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Protein-Rich Rafts in Hybrid Polymer/Lipid Giant Unilamellar Vesicles.Biomacromolecules · 2024Article
- Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Structure-Based Evaluation of Hybrid Lipid-Polymer Nanoparticles: The Role of the Polymeric Guest.Polymers · 2024Article
- Review
- Microfluidic synthesis of multilayered lipid-polymer hybrid nanoparticles for the formulation of low solubility drugs.Soft matter · 2023Article
- Tailoring a Solvent-Assisted Method for Solid-Supported Hybrid Lipid-Polymer Membranes.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Aqueous Heat Method for the Preparation of Hybrid Lipid-Polymer Structures: From Preformulation Studies to Protein Delivery.Biomedicines · 2022Article
- Current Perspectives on Synthetic Compartments for Biomedical Applications.International journal of molecular sciences · 2022Review
- Polymer-Lipid Hybrid Materials.Chemical reviews · 2021Review
- Recent Advancements in Polymer/Liposome Assembly for Drug Delivery: From Surface Modifications to Hybrid Vesicles.Polymers · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Phospholipid (PL) membranes are ubiquitous in nature and their phase behavior has been extensively studied. Lipids assemble in a variety of structures and external stimuli can activate a quick switch between them. Amphiphilic block copolymers (BCPs) can self-organize in analogous structures but are mechanically more robust and transformations are considerably slower. The combination of PL dynamical behavior with BCP chemical richness could lead to new materials for applications in bioinspired separation membranes and drug delivery. It is timely to underpin the phase behavior of these hybrid systems and a few recent studies have revealed that PL-BCP membranes display synergistic structural, phase-separation, and dynamical properties not seen in pure components. One example is phase-separation in the membrane plane, which seems to be strongly affected by the ability of the PL to form lamellar phases with ordered alkyl chains. In this paper we focus on a rather less explored design handle which is the crystalline properties of the BCP component. Using a combination of confocal laser scanning microscopy and X-ray scattering we show that hybrid membranes of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and methoxy-poly(ethylene glycol)-
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