ArticleJournal of experimental botany2020
The amino acid transporter AAP1 mediates growth and grain yield by regulating neutral amino acid uptake and reallocation in Oryza sativa.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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53 citing papers in PubMed, 158 citations in OpenAlex.
- Cereal protein biofortification at the interface of nutrition, yield and sustainability.Nature plants · 2026Review
- Physiological and Molecular Mechanisms of Nitrogen Regulation on Grain Quality in Cereal Crops at Later Stages.International journal of molecular sciences · 2026Review
- Cell wall remodeling and inositol metabolism coexpression modules associated with nut size in Carya illinoinensis cvs. 'Mahan' and 'Tiny tim'.Scientific reports · 2026Article
- Regulation of grain protein content by the amino acid permease gene OsAAP4 in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- From rhizome diffusion to programmable architecture: a systems framework for controllable spatial expansion in bamboo and other clonal plants.Frontiers in plant science · 2026Review
- Comprehensive GWAS and transcriptome analysis discovered new candidate genes for powdery mildew response in pea (Pisum sativum L.).BMC plant biology · 2025Article
- Genome-Wide Association Studies Identify OsNLP6 as a Key Regulator of Nitrogen Use Efficiency in Rice.Plant biotechnology journal · 2025Article
- Amino Acid Regulation in Rice: Integrated Mechanisms and Agricultural Applications.Rice (New York, N.Y.) · 2025Review
- Genetic Improvement and Functional Characterization of AAP1 Gene for Enhancing Nitrogen Use Efficiency in Maize.Plants (Basel, Switzerland) · 2025Article
- A Multi-omics Approach Reveals the Effects of Bio- and Chemical- Pesticides on Rice Yield and Quality under Disease Stress.Rice (New York, N.Y.) · 2025Article
- Genome-wide identification of the AAT gene family in quinoa and analysis of its expression pattern under abiotic stresses.BMC genomics · 2025Article
- Mining of Root-Specific Expression Genes and Their Core Cis-Regulatory Elements in Plants.International journal of molecular sciences · 2025Article
- Transcription factor OsMYB2 triggers amino acid transporter OsANT1 expression to regulate rice growth and salt tolerance.Plant physiology · 2025Article
- Genome-wide identification ofFrontiers in genetics · 2025Article
- Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum.Frontiers in genetics · 2025Article
- Research progress on the function and regulatory pathways of amino acid permeases in fungi.World journal of microbiology & biotechnology · 2024Review
- High Overexpression ofInternational journal of molecular sciences · 2024Article
- Blocking of amino acid transporter OsAAP7 promoted tillering and yield by determining basic and neutral amino acids accumulation in rice.BMC plant biology · 2024Article
- Article
- Mitigating growth-stress tradeoffs via elevated TOR signaling in rice.Molecular plant · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen (N) is a major element necessary for crop yield. In most plants, organic N is primarily transported in the form of amino acids. Here, we show that amino acid permease 1 (AAP1) functions as a positive regulator of growth and grain yield in rice. We found that the OsAAP1 gene is highly expressed in rice axillary buds, leaves, and young panicles, and that the OsAAP1 protein is localized to both the plasma membrane and the nuclear membrane. Compared with the wild-type ZH11, OsAAP1 overexpression (OE) lines exhibited increased filled grain numbers as a result of enhanced tillering, while RNAi and CRISPR (clustered regularly interspaced short palindromic repeat; Osaap1) knockout lines showed the opposite phenotype. In addition, OsAAP1-OE lines had higher concentrations of neutral and acidic amino acids, but lower concentrations of basic amino acids in the straw. An exogenous treatment with neutral amino acids promoted axillary bud outgrowth more strongly in the OE lines than in the WT, RNAi, or Osaap1 lines. Transcriptome analysis of Osaap1 further demonstrated that OsAAP1 may affect N transport and metabolism, and auxin, cytokinin, and strigolactone signaling in regulating rice tillering. Taken together, these results support that increasing neutral amino acid uptake and reallocation via OsAAP1 could improve growth and grain yield in rice.
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