Evidence map›Paper›PMID 32484909›Full record

ArticleBiotechnology and bioengineering2020

Exosomes derived from chemically induced human hepatic progenitors inhibit oxidative stress induced cell death.

Sujin Hyung, Jaemin Jeong, Kyusoon Shin, Ju Young Kim, Ji-Hye Yim, Chan Jong Yu, Hyun Suk Jung, Kyung-Gyun Hwang, Dongho Choi, Jong Wook Hong

Open access · hybridAbstract read
In one paragraph

Article in Biotechnology and bioengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Crosstalk between Oxidative Stress and Exosomes.Oxidative medicine and cellular longevity · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Roles of Exosomes in Ocular Diseases.International journal of nanomedicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sujin HyungCenter for Exosome & Bioparticulate Research, Hanyang University, Gyeonggi-do, Korea.ORCID 0000-0003-1192-0972
Jaemin JeongHY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul, Korea.
Kyusoon ShinCenter for Exosome & Bioparticulate Research, Hanyang University, Gyeonggi-do, Korea.
Ju Young KimCenter for Exosome & Bioparticulate Research, Hanyang University, Gyeonggi-do, Korea.
Ji-Hye YimHY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul, Korea.
Chan Jong YuDivision of Chemistry and Biochemistry, Kangwon National University, Chuncheon, Korea.
Hyun Suk JungDivision of Chemistry and Biochemistry, Kangwon National University, Chuncheon, Korea.
Kyung-Gyun HwangDepartment of Dentistry/Oral & Maxillofacial Surgery, Collage of Medicine, Hanyang University, Seoul, Korea.
Dongho ChoiHY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul, Korea.
Jong Wook HongCenter for Exosome & Bioparticulate Research, Hanyang University, Gyeonggi-do, Korea.ORCID 0000-0001-9529-5400
Korea Aerospace University · KRHanyang University Medical Center · KRKangwon National University · KRHanyang University · KR

Funding

National Research Foundation of Korea 2017R1A5A2015395National Research Foundation of Korea 2018M3A9H1023323National Research Foundation of Korea 2018M3A9H1023910National Research Foundation of Korea 2018R1A2B6005354
6 · The paper itself

Abstract

The emerging field of regenerative medicine has revealed that the exosome contributes to many aspects of development and disease through intercellular communication between donor and recipient cells. However, the biological functions of exosomes secreted from cells have remained largely unexplored. Here, we report that the human hepatic progenitor cells (CdHs)-derived exosome (EXO

Indexed as

AntioxidantsExosomesCell DeathCells, CulturedCell SurvivalChildFemaleHepatocytesHumansOxidative StressStem CellsAntioxidantsantioxidant activitycell survivalexosome therapyhuman hepatic progenitor cells-derived exosome (EXOhCdHs)liver disease

Identifiers

PMID32484909
PMCPMC7496643
OpenAlexW3031718314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.