Evidence map›Paper›PMID 32484786›Full record

ArticleAging2020

Nomogram for the prediction of diabetic nephropathy risk among patients with type 2 diabetes mellitus based on a questionnaire and biochemical indicators: a retrospective study.

Yuhong Hu, Rong Shi, Ruohui Mo, Fan Hu

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Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

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0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  6. A nomograph model for predicting the risk of diabetes nephropathy.International urology and nephrology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuhong HuSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Rong ShiSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ruohui MoSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fan HuSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDevelop a diabetic nephropathy incidence risk nomogram in a Chinese population with type 2 diabetes mellitus.

resultsPredictors included systolic blood pressure, diastolic blood pressure, fasting blood glucose, glycosylated hemoglobin A1c, total triglycerides, serum creatinine, blood urea nitrogen and body mass index. The model displayed medium predictive power with a C-index of 0.744 and an area under curve of 0.744. Internal verification of C-index reached 0.737. The decision curve analysis showed the risk threshold was 20%. The value of net reclassification improvement and integrated discrimination improvement were 0.131, 0.05, and that the nomogram could be applied in clinical practice.

conclusionDiabetic nephropathy incidence risk nomogram incorporating 8 features is useful to predict diabetic nephropathy incidence risk in type 2 diabetes mellitus patients.

methodsQuestionnaires, physical examinations and biochemical tests were performed on 3489 T2DM patients in six communities in Shanghai. LASSO regression was used to optimize feature selection by running cyclic coordinate descent. Logistic regression analysis was applied to build a prediction model incorporating the selected features. The C-index, calibration plot, curve analysis, forest plot, net reclassification improvement, integrated discrimination improvement and internal validation were used to validate the discrimination, calibration and clinical usefulness of the model.

Indexed as

NomogramsAdultAgedAged, 80 and overBlood GlucoseBlood PressureBlood Urea NitrogenBody Mass IndexChinaCreatinineDiabetes Mellitus, Type 2Diabetic NephropathiesFemaleGlycated HemoglobinHumansIncidenceBlood GlucoseCreatinineGlycated Hemoglobinhemoglobin A1c protein, humanTriglyceridesdiabetic nephropathynomogrampredictorsrisk factorstype 2 diabetes mellitus

Identifiers

PMID32484786
PMCPMC7346021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.