Evidence map›Paper›PMID 32484742›Full record

ArticleAIDS patient care and STDs2020

HIV Stigma, Depressive Symptoms, and Substance Use.

Valerie A Earnshaw, Lisa A Eaton, Zachary K Collier, Ryan J Watson, Jessica L Maksut, Katherine B Rucinski, John F Kelly, Seth C Kalichman

Open access · greenAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Valerie A EarnshawDepartment of Human Development and Family Sciences, University of Delaware, Newark, Delaware, USA.
Lisa A EatonInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, Connecticut, USA.
Zachary K CollierSchool of Education, University of Delaware, Newark, Delaware, USA.
Ryan J WatsonInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, Connecticut, USA.
Jessica L MaksutDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Katherine B RucinskiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
John F KellyRecovery Research Institute, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Seth C KalichmanInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, Connecticut, USA.
University of Connecticut · USJohns Hopkins University · USUniversity of Delaware · USHarvard University · US

Funding

Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
Unified Intervention to Impact HIV Care ContinuumR01DA043068 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI EATON, LISA A, KALICHMAN, SETH C · 2016 to 2020
$3.7M
Mentoring in Patient-Oriented Addiction ResearchK24AA022136 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI KELLY, JOHN F. · 2014 to 2023
$1.8M
PrEP and substance use among sexual minority young adultsK01DA047918 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI WATSON, RYAN J · 2019 to 2023
$952k
Understanding and Addressing Disclosure to Members of Social Networks among People Recovering from Substance Use DisordersK01DA042881 · NIDA · UNIVERSITY OF DELAWARE · PI EARNSHAW, VALERIE ANN · 2017 to 2020
$756k
NIAAA NIH HHS K24 AA022136NIAID NIH HHS T32 AI102623NIDA NIH HHS K01 DA042881NIDA NIH HHS K01 DA047918NIDA NIH HHS R01 DA043068
6 · The paper itself

Abstract

Substance use problems undermine HIV treatment and secondary prevention efforts. Research is needed to better understand predictors of substance use among people living with HIV (PLWH). We examined whether internalized stigma and enacted HIV stigma are associated with three indicators of substance use among PLWH, including numbers of (1) substances used, (2) substances used at moderate to high risk, and (3) times substances were used before sex, through the mediator of depressive symptoms. Participants included 358 PLWH aged 18-35 years from Georgia, United States. At baseline, participants completed measures of internalized and enacted stigma, depressive symptoms, and substance use severity. Substance use was additionally tested with urinalysis. Following baseline, participants reported their use of substances before sex for 28 days through daily text messaging. Data were analyzed using path analysis in R. On average, participants tested positive for 1.24 (range: 0-6) substances used, reported moderate to high risk on 2.01 (range: 0-8) substances, and reported using substances 1.57 (range: 0-20) times before sex over 28 days. Internalized stigma and enacted stigma were associated with greater depressive symptoms, and depressive symptoms were associated with all three indicators of substance use. Moreover, the indirect effects between internalized and enacted stigma with indicators of substance use were significant, suggesting that depressive symptoms partially mediated associations between stigma and substance use. Interventions may be needed to address both stigma and depressive symptoms among PLWH to reduce substance use and support HIV treatment and prevention efforts.

Indexed as

Social StigmaAdolescentAdultAnti-HIV AgentsDepressionFemaleGeorgiaHIV InfectionsHumansMaleMedication AdherenceSubstance-Related DisordersUnited StatesYoung AdultAnti-HIV AgentsaddictiondepressionHIVstigmasubstance use

Identifiers

PMID32484742
PMCPMC7262648
OpenAlexW3031906990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.