ArticleAmerican journal of physiology. Endocrinology and metabolism2020
Adipose tissue macrophage burden, systemic inflammation, and insulin resistance.
Article in American journal of physiology. Endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- One week of overeating upregulates angiogenic and lipolytic gene expression in human subcutaneous adipose tissue from exercise trained and untrained adults.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2022Trial
- Adipose Tissue Immunosuppressive T Cells Regulate Atherosclerosis Development and Liver Fat Accumulation in Obesity.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Nutraceuticals as modulators of genetic, epigenetic and hormonal factors in obesity.European journal of clinical nutrition · 2026Review
- T cells are elevated in abdominal and femoral adipose tissue in females with type 2 diabetes.Journal of the Endocrine Society · 2026Article
- Anti-inflammatory drug and prebiotics alter metabolic inflammation in fattening ground squirrels and outbred mice.Frontiers in physiology · 2026Article
- Perivascular adipocyte size is related to the lipid profile and inflammatory changes in a healthy population.Adipocyte · 2025Article
- Identification of SDC4 as a potential target for obesity via integrated analysis of the lncRNA-miRNA-mRNA network in visceral adipose tissue.Adipocyte · 2025Article
- Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity.The Journal of physiology · 2025Article
- Acute session of three endurance exercise intensities alters subcutaneous adipose tissue transcriptome in regular exercisers.bioRxiv : the preprint server for biology · 2025Article
- Human Adipose Tissue Metabolism in Obesity.Journal of obesity & metabolic syndrome · 2025Review
- Polychlorinated biphenyls induce immunometabolic switch of antiinflammatory macrophages toward an inflammatory phenotype.PNAS nexus · 2025Article
- Pericoronary adipose tissue inflammation mediates the atherogenic effects of lipids on multivessel coronary artery disease: a CCTA-based radiomics analysis.Frontiers in cardiovascular medicine · 2025Article
- Years of endurance exercise training remodel abdominal subcutaneous adipose tissue in adults with overweight or obesity.Nature metabolism · 2024Article
- Exercise as a tool to mitigate metabolic disease.American journal of physiology. Cell physiology · 2024Review
- Review
- An Atlas of Promoter Chromatin Modifications and HiChIP Regulatory Interactions in Human Subcutaneous Adipose-Derived Stem Cells.International journal of molecular sciences · 2023Article
- Endoplasmic Reticulum Stress and Its Impact on Adipogenesis: Molecular Mechanisms Implicated.Nutrients · 2023Review
- Adipocytes in the Uterine Wall during Experimental Healing and in Cesarean Scars during Pregnancy.International journal of molecular sciences · 2023Article
- Dibenzoylmethane ameliorates adiposity-mediated neuroinflammatory response and inflammation-mediated neuronal cell death in mouse microglia and neuronal cells.Food science and biotechnology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Adipose tissue inflammation, as defined by macrophage accumulation, is proposed to cause insulin resistance and systemic inflammation. Because the strength of this relationship for humans is unclear, we tested whether adipose tissue macrophage (ATM) burden is correlated with these health indicators. Using immunohistochemistry, we measured abdominal subcutaneous CD68+ (total ATM), CD14+ (proinflammatory/M1), and CD206+ (anti-inflammatory/M2) ATM in 97 volunteers (BMI 20-38 kg/m
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.