Evidence map›Paper›PMID 32484439›Full record

RevieweLife2020

Hyperalignment: Modeling shared information encoded in idiosyncratic cortical topographies.

James V Haxby, J Swaroop Guntupalli, Samuel A Nastase, Ma Feilong

Abstract readReview
In one paragraph

Review in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Trial
  2. Review
  3. Brain Mechanisms of Lexicality in Bilingual Emotion Processing.bioRxiv : the preprint server for biology · 2026
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  6. Review
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  17. Familial transmission of neural representations for mental arithmetic across two generations.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James V HaxbyCenter for Cognitive Neuroscience, Dartmouth College, Hanover, United States.ORCID 0000-0002-6558-3118
J Swaroop GuntupalliVicarious AI, Union City, United States.ORCID 0000-0002-0677-5590
Samuel A NastasePrinceton Neuroscience Institute, Princeton, United States.ORCID 0000-0001-7013-5275
Ma FeilongCenter for Cognitive Neuroscience, Dartmouth College, Hanover, United States.ORCID 0000-0002-6838-3971

Funding

National Science Foundation 1607845National Science Foundation 1835200
6 · The paper itself

Abstract

Information that is shared across brains is encoded in idiosyncratic fine-scale functional topographies. Hyperalignment captures shared information by projecting pattern vectors for neural responses and connectivities into a common, high-dimensional information space, rather than by aligning topographies in a canonical anatomical space. Individual transformation matrices project information from individual anatomical spaces into the common model information space, preserving the geometry of pairwise dissimilarities between pattern vectors, and model cortical topography as mixtures of overlapping, individual-specific topographic basis functions, rather than as contiguous functional areas. The fundamental property of brain function that is preserved across brains is information content, rather than the functional properties of local features that support that content. In this Perspective, we present the conceptual framework that motivates hyperalignment, its computational underpinnings for joint modeling of a common information space and idiosyncratic cortical topographies, and discuss implications for understanding the structure of cortical functional architecture.

Indexed as

Models, NeurologicalAlgorithmsCerebral CortexConnectomeElectroencephalographyHumansMagnetoencephalographyNerve Netcortexfunctional connectivityhyperalignmentindividual differencesneurosciencepopulation responsetopography

Identifiers

PMID32484439
PMCPMC7266639

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.