Evidence map›Paper›PMID 32484065›Full record

ArticlePain management2020

Chronic pain in people with HIV: a common comorbidity and threat to quality of life.

Victoria J Madden, Romy Parker, Burel R Goodin

Open access · hybridAbstract read
In one paragraph

Article in Pain management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 75 citations in OpenAlex.

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  2. Pitavastatin Is Well-Tolerated With no Detrimental Effects on Physical Function.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025 · on this map
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Victoria J MaddenDepartment of Anaesthesia & Perioperative Medicine, Neuroscience Institute, University of Cape Town, Cape Town, Western Cape, South Africa.
Romy ParkerDepartment of Anaesthesia & Perioperative Medicine, Neuroscience Institute, University of Cape Town, Cape Town, Western Cape, South Africa.
GTx (United States) · USMental Health Research Institute · AUUniversity of Cape Town · ZA

Funding

The Impact of Insomnia on Pain, Physical Function, and Inflammation in HIVR01HL147603 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2019 to 2022
$2.8M
Psychosocial distress, inflammatory reactivity and central sensitization in the pathway to HIV-related pain: characterizing the associations and developing a pragmatic, coping-focused intervention.K43TW011442 · FIC · UNIVERSITY OF CAPE TOWN · PI MADDEN, VICTORIA JOY · 2019 to 2023
$674k
FIC NIH HHS K43 TW011442NHLBI NIH HHS R01 HL147603
6 · The paper itself

Abstract

Evidence indicates that over half of all people with HIV (PWH) will experience nonmalignant chronic pain throughout their lifetimes, with increasing prevalence as they age. Peripheral neuropathy resulting from the neurotoxic effects of HIV itself and the medications used to treat HIV were widely considered the primary cause of acute and chronic pain early on in the antiretroviral treatment era. However, recent studies suggest a predominance of non-neuropathic (e.g., musculoskeletal) pain in PWH with uncertain etiology. Chronic pain is often widespread in PWH, affecting multiple body locations. Additional research is needed to better understand contributors to chronic pain in PWH, which is likely to include biological (e.g., immune dysregulation), psychological (e.g., substance abuse) and social (e.g., stigma) factors.

Indexed as

Quality of LifeAdultChronic PainComorbidityHealth Services AccessibilityHIV InfectionsHumansMusculoskeletal PainPrevalenceSocial StigmaSocial Supportaccess to carebiopsychosocialHIVinflammationmental healthpainprevalencequality of lifesocial supportstigma

Identifiers

PMID32484065
PMCPMC7421257
OpenAlexW3030500153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.