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ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2020

Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Missed Abortion.

Ismail Biyik, Mustafa Albayrak, Fatih Keskin

Open access · diamondAbstract read
In one paragraph

Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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  14. Predictive value of NLR and PLR in missed miscarriage.Journal of clinical laboratory analysis · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ismail BiyikDepartment of Obstetrics and Gynecology, School of Medicine, Kütahya Health Sciences University, Kütahya, Turkey.ORCID 0000-0001-6111-9302
Mustafa AlbayrakDepartment of Obstetrics and Gynecology, Florence Nightingale Hospital, Istanbul, Turkey.ORCID 0000-0003-2941-7574
Fatih KeskinPrivate Balkan Hospital, Edirne, Turkey.ORCID 0000-0003-3569-0307
Istanbul Florence Nightingale Hospital · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMissed abortion occurs in ∼ 15% of all clinical pregnancies. The pathogenesis is not clearly known. However, defective placentation resulting in maternal systemic inflammatory response is considered responsible for missed abortion. Platelet lymphocyte ratio (PLR) and neutrophil lymphocyte ratio (NLR) are increasingly cited parameters of inflammation in the literature. However, no study evaluated the PLR and NLR rates in missed abortions so far. The aim of the present study is to investigate whether complete blood count (CBC) inflammatory parameters such as NLR and PLR are increased in patients with missed abortion.

methodsMedical records of 40 pregnant women whose gestation ended in missed abortion at between 6 and14 weeks of gestation and of 40 healthy pregnant women were collected and compared retrospectively. The groups were compared regarding hemoglobin, hematocrit, platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), PLR and NLR.

resultsPlatelet distribution width, NLR and PLR values were higher in the missed abortion group compared with the healthy pregnant women group (rates are

conclusionThe PDW, NLR and PLR values of the missed abortion group were reported high; and MPV values were reported low in the present study. These findings may help to speculate a defective placentation in the pathogenesis of missed abortion.

Indexed as

LymphocytesNeutrophilsPlatelet CountAbortion, MissedAdultBiomarkersFemaleHumansMedical RecordsPregnancyPregnancy Trimester, FirstRetrospective StudiesROC CurveSensitivity and SpecificityBiomarkers

Identifiers

PMID32483803
PMCPMC10316850
OpenAlexW3030814834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.