Evidence map›Paper›PMID 32483663›Full record

ArticleJournal of clinical immunology2020

The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery.

Tri Giang Phan, Paul E Gray, Melanie Wong, Rebecca Macintosh, Leslie Burnett, Stuart G Tangye, CIRCA

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tri Giang PhanImmunity and Inflammation Theme, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, New South Wales, 2010, Australia. t.phan@garvan.org.au.
Paul E GrayDepartment of Immunology and Allergy, Sydney Children's Hospital, Randwick, Sydney, New South Wales, Australia.
Melanie WongDepartment of Immunology and Allergy, Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Rebecca MacintoshSchool of Women's and Children Health, Faculty of Medicine, UNSW Sydney, Sydney, New South Wales, Australia.
Leslie BurnettSt Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, New South Wales, Australia.
Stuart G TangyeImmunity and Inflammation Theme, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, New South Wales, 2010, Australia.ORCID 0000-0002-5360-5180
CIRCA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Clinical Immunogenomics Research Consortium Australasia (CIRCA) crowdsources expertise in medicine, genomics, data science, and fundamental biology to diagnose and treat patients with rare inborn errors of immunity. This distributed network model operates free of geographic borders and allows rapid progression through the full research/translation/clinical management pipeline, from initial gene variant discovery, through functional validation, and on to precision mechanism-based treatment of patients throughout Australia and New Zealand. The model is scalable and applicable to other rare diseases where clinical experience and scientific know-how are limited, and enables efficient delivery of genomics for all.

Indexed as

Models, EconomicAustralasiaCommunity NetworksDelivery of Health CareGenomicsHigh-Throughput Nucleotide SequencingHumansImmunogeneticsPrecision MedicinePrimary Immunodeficiency DiseasesTranslational Research, Biomedical

Identifiers

PMID32483663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.