Evidence map›Paper›PMID 32483557›Full record

ArticleCell reports. Medicine2020

The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.

Megan Garland, Andrew J Hryckowian, Martina Tholen, Kristina Oresic Bender, William W Van Treuren, Sebastian Loscher, Justin L Sonnenburg, Matthew Bogyo

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Re-framing the importance of Group BInfection and immunity · 2024
    Review
  6. Clinical microbiology reviews · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. SelectedMolecules (Basel, Switzerland) · 2023
    Article
  14. Article
  15. International journal of molecular sciences · 2023
    Article
  16. Antibacterial Activity of Ebselen.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Capturing the environment of the Clostridioides difficile infection cycle.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Megan GarlandCancer Biology Program, Stanford School of Medicine, Stanford, CA 94305 USA.
Andrew J HryckowianDepartment of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA 94305, USA.
Martina TholenDepartment of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.
Kristina Oresic BenderDepartment of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.
William W Van TreurenDepartment of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA 94305, USA.
Sebastian LoscherDepartment of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.
Justin L SonnenburgDepartment of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA 94305, USA.
Matthew BogyoCancer Biology Program, Stanford School of Medicine, Stanford, CA 94305 USA.
Stanford Medicine · US

Funding

Impact of Diet on Intestinal Microbiota-Host DynamicsR01DK085025 · NIDDK · STANFORD UNIVERSITY · PI JUSTIN L SONNENBURG · 2010 to 2026
$6.4M
Staphylococcus serine hydrolases as targets for therapeutic and imaging contrast agentsR01EB026332 · NIBIB · STANFORD UNIVERSITY · PI BOGYO, MATTHEW · 2018 to 2021
$1.4M
Development of non-antibiotic therapeutics for Clostridium difficile infection (CDI)R56AI127455 · NIAID · STANFORD UNIVERSITY · PI BOGYO, MATTHEW · 2017 to 2017
$393k
NIAID NIH HHS R56 AI127455NIBIB NIH HHS R01 EB026332NIDDK NIH HHS R01 DK085025
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsClostridioides difficileClostridium InfectionsCricetinaeDisease Models, AnimalDysbiosisEnterocolitis, PseudomembranousFemaleGastrointestinal MicrobiomeInflammationIsoindolesMaleMesocricetusMiceOrganoselenium CompoundsebselenIsoindolesOrganoselenium Compounds

Identifiers

PMID32483557
PMCPMC7263476
OpenAlexW3018086435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.