Evidence map›Paper›PMID 32483540›Full record

ArticleRestorative dentistry & endodontics2020

Antimicrobial efficacy of QMix on

Benjamin Syek Hur Lim, Abhishek Parolia, Margaret Soo Yee Chia, Jayakumar Jayaraman, Venkateshbabu Nagendrababu

Open access · diamondAbstract read
In one paragraph

Article in Restorative dentistry & endodontics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Journal of inflammation research · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. AnBiomaterial investigations in dentistry · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Benjamin Syek Hur LimSchool of Dentistry, International Medical University, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-5074-0953
Abhishek ParoliaDivision of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-3364-6743
Margaret Soo Yee ChiaSchool of Dentistry, International Medical University, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-0590-4872
Jayakumar JayaramanDepartment of Developmental Dentistry, University of Texas Health School of Dentistry, San Antonio, TX, USA.ORCID https://orcid.org/0000-0003-1737-6891
Venkateshbabu NagendrababuDivision of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0003-3783-3156
IMU University · MYThe University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against MATERIALS AND

methodsThe research question was developed by using population, intervention, comparison, outcome, and study design framework. The literature search was performed using 3 electronic databases: PubMed, Scopus, and EBSCOhost until October 2019. The additional hand search was performed from the reference list of the eligible studies. The risk of bias of the studies was independently appraised using the revised Cochrane Risk of Bias tool (RoB 2.0).

resultsFourteen studies were included in this systematic review. The overall risk of bias for the selected studies was moderate. QMix was found to have a higher antimicrobial activity compared to 2% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), mixture of tetracycline isonomer, an acid and a detergent (MTAD), 0.2% Cetrimide, SilverSol/H2O2, HYBENX, and grape seed extract (GSE). QMix had higher antibacterial efficacy compared to NaOCl, only when used for a longer time (10 minutes) and with higher volume (above 3 mL).

conclusionsQMix has higher antibacterial activity than 17% EDTA, 2% CHX, MTAD, 0.2% Cetrimide, SilverSol/H2O2, HYBENX, GSE and NaOCl with lower concentration. To improve the effectiveness, QMix is to use for a longer time and at a higher volume.

trial registrationPROSPERO International prospective register of systematic reviews Identifier: CRD42018096763.

Indexed as

ChlorhexidineEnterococcus faecalisQMixroot canal treatmentsystematic review

Identifiers

PMID32483540
PMCPMC7239686
OpenAlexW3011248324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.