Evidence map›Paper›PMID 32483483›Full record

ReviewCell & bioscience2020

Extracellular vesicles derived from different sources of mesenchymal stem cells: therapeutic effects and translational potential.

Jiaxin Cai, Junyong Wu, Jiemin Wang, Yongjiang Li, Xiongbin Hu, Shifu Luo, Daxiong Xiang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell & bioscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaxin Cai1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Junyong Wu1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Jiemin Wang1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Yongjiang Li1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Xiongbin Hu1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Shifu Luo4Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
Daxiong Xiang1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) were known to have excellent properties in cell therapy. However, the risk of immune rejection associated with cell transplant therapy hampers its use. Extracellular vesicles secreted by MSCs derived from different sources that contain therapeutic molecules such as RNA and proteins, which is a novel strategy for cell-free therapy. Recently, researches show EVs from MSCs (MSC-EVs) of different sources have special functions and effects on different diseases. Here, we collected these researches and compared them to each other. In addition, their potential and possible application in clinical treatment are described.

Indexed as

ExosomesExtracellular vesiclesMesenchymal stem cells

Identifiers

PMID32483483
PMCPMC7245623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.