Evidence map›Paper›PMID 32483435›Full record

ArticleTheranostics2020

Instant labeling of therapeutic cells for multimodality imaging.

Hossein Nejadnik, Kyung Oh Jung, Ashok J Theruvath, Louise Kiru, Anna Liu, Wei Wu, Todd Sulchek, Guillem Pratx, Heike E Daldrup-Link

Abstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. In vivo imaging of nanoparticle-labeled CAR T cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Review
  11. Article
  12. Rapid Magneto-Sonoporation of Adipose-Derived Cells.Materials (Basel, Switzerland) · 2021
    Article
  13. Paving the way for small-molecule drug discovery.American journal of translational research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hossein NejadnikDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, 94305, USA.
Kyung Oh JungDepartment of Radiation Oncology, Stanford University, CA, 94305, USA.
Ashok J TheruvathDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, 94305, USA.
Louise KiruDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, 94305, USA.
Anna LiuDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Wei WuDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, 94305, USA.
Todd SulchekDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Guillem PratxDepartment of Radiation Oncology, Stanford University, CA, 94305, USA.
Heike E Daldrup-LinkDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, 94305, USA.

Funding

Monitoring of Stem Cell Engraftment in Arthritic Joints with MR ImagingR01AR054458 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DALDRUP-LINK, HEIKE ELIZABETH · 2008 to 2021
$6.7M
Instant Stem Cell Labeling with a new Microfluidic DeviceR21AR075863 · NIAMS · STANFORD UNIVERSITY · PI DALDRUP-LINK, HEIKE ELIZABETH · 2019 to 2020
$379k
NIAMS NIH HHS R01 AR054458NIAMS NIH HHS R21 AR075863
6 · The paper itself

Abstract

Autologous therapeutic cells are typically harvested and transplanted in one single surgery. This makes it impossible to label them with imaging biomarkers through classical transfection techniques in a laboratory. To solve this problem, we developed a novel microfluidic device, which provides highly efficient labeling of therapeutic cells with imaging biomarkers through mechanoporation.

Indexed as

Adipose TissueAnimalsBiomarkersCells, CulturedFluorodeoxyglucose F18Magnetic Resonance ImagingMagnetite NanoparticlesMultimodal ImagingPositron-Emission TomographyStaining and LabelingStem CellsSwineBiomarkersFluorodeoxyglucose F18Magnetite Nanoparticles18F-FDGin vivo cell trackingiron oxide nanoparticlesmechanoporationmicrofluidic device

Identifiers

PMID32483435
PMCPMC7255004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.