Evidence map›Paper›PMID 32483414›Full record

ArticleTheranostics2020

Skipping of exon 10 in

Lianghua Shen, Sijia Lei, Bin Zhang, Shuaiguang Li, Luyuan Huang, Alexander Czachor, Mason Breitzig, Yuman Gao, Meiyan Huang, Xuemei Mo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential.Journal of cellular and molecular medicine · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Targeting RNA splicing modulation: new perspectives for anticancer strategy?Journal of experimental & clinical cancer research : CR · 2025
    Review
  12. Article
  13. Article
  14. PTBP1 as a potential regulator of disease.Molecular and cellular biochemistry · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Lianghua ShenInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Sijia LeiInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Bin ZhangInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Shuaiguang LiInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Luyuan HuangGuangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Alexander CzachorDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd, MDC 19, Tampa, FL 33612, USA.
Mason BreitzigDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd, MDC 19, Tampa, FL 33612, USA.
Yuman GaoInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Meiyan HuangInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Xuemei MoInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Qing ZhengInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Hanxiao SunInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Feng WangInstitute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Jinan University · CNUniversity of South Florida · USChinese Academy of Sciences · CNWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Axl gene is known to encode for a receptor tyrosine kinase involved in the metastasis process of cancer. In this study, we investigated the underlying molecular mechanism of Axl alternative splicing.

Indexed as

Alternative SplicingAnimalsAxl Receptor Tyrosine KinaseCarcinoma, HepatocellularCell Line, TumorCell MovementCell ProliferationExonsGene Expression Regulation, NeoplasticHeterogeneous-Nuclear RibonucleoproteinsHumansLiverLiver NeoplasmsMaleMiceMice, Inbred BALB CAxl Receptor Tyrosine KinaseHeterogeneous-Nuclear RibonucleoproteinsPolypyrimidine Tract-Binding ProteinProto-Oncogene ProteinsPTBP1 protein, humanReceptor Protein-Tyrosine KinasesRNA, MessengerRNA PrecursorsSplicing Factor U2AFU2AF2 protein, humanalternative splicingAxlliver cancer cellsPTBP1tumor metastasis

Identifiers

PMID32483414
PMCPMC7255001
OpenAlexW3023386144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.