Evidence map›Paper›PMID 32483267›Full record

ArticleScientific reports2020

On the Aggregation and Nucleation Mechanism of the Monoclonal Antibody Anti-CD20 Near Liquid-Liquid Phase Separation (LLPS).

Elvira Pantuso, Teresa F Mastropietro, Maria L Briuglia, Charline J J Gerard, Efrem Curcio, Joop H Ter Horst, Fiore P Nicoletta, Gianluca Di Profio

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The Multivalent Polyampholyte Domain of Nst1, a P-Body-AssociatedInternational journal of molecular sciences · 2022
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elvira PantusoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci Edificio Polifunzionale, 87036, Rende, CS, Italy.
Teresa F MastropietroNational Research Council of Italy (CNR) - Institute on Membrane Technology (ITM), Via P. Bucci Cubo 17/C, 87036, Rende, CS, Italy.
Maria L BriugliaEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC), Strathclyde Institute of Pharmacy and Biomedical Sciences, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Charline J J GerardEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC), Strathclyde Institute of Pharmacy and Biomedical Sciences, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Efrem CurcioDepartment of Environmental Engineering (DIAm), University of Calabria, Via P. Bucci Cubo 45/A, 87036, Rende, CS, Italy.
Joop H Ter HorstEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC), Strathclyde Institute of Pharmacy and Biomedical Sciences, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Fiore P NicolettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci Edificio Polifunzionale, 87036, Rende, CS, Italy. fiore.nicoletta@unical.it.
Gianluca Di ProfioNational Research Council of Italy (CNR) - Institute on Membrane Technology (ITM), Via P. Bucci Cubo 17/C, 87036, Rende, CS, Italy. g.diprofio@itm.cnr.it.
University of Calabria · ITUniversity of Strathclyde · GBInstitute on Membrane Technology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The crystallization of Anti-CD20, a full-length monoclonal antibody, has been studied in the PEG400/Na

Indexed as

Antibodies, MonoclonalAntigens, CD20Circular DichroismCrystallizationHumansHydrogen-Ion ConcentrationLiquid-Liquid ExtractionPolyethylene GlycolsSulfatesWaterAntibodies, MonoclonalAntigens, CD20polyethylene glycol 400Polyethylene Glycolssodium sulfateSulfatesWater

Identifiers

PMID32483267
PMCPMC7264149
OpenAlexW3030739782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.