Evidence map›Paper›PMID 32483221›Full record

ArticleEuropean journal of clinical nutrition2020

The significant effect on musculoskeletal metabolism and bone density of the Eastern Mediterranean Christian Orthodox Church fasting.

Nikolaos E Rodopaios, George E Manolarakis, Alexandra-Aikaterini Koulouri, Eleni Vasara, Sousana K Papadopoulou, Petros Skepastianos, Emmanouil Dermitzakis, Maria Hassapidou, Manolis K Linardakis, Anthony G Kafatos

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Article in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Nikolaos E RodopaiosDepartment of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece. nikow1966@yahoo.gr.ORCID http://orcid.org/0000-0001-7710-6231
George E ManolarakisDepartment of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece.ORCID http://orcid.org/0000-0003-1093-7350
Alexandra-Aikaterini KoulouriDepartment of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece.
Eleni VasaraLaboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Sousana K PapadopoulouDepartment of Nutritional Sciences and Dietetics, International Hellenic University, Thermi, Greece.
Petros SkepastianosDepartment of Medical Laboratory Studies, International Hellenic University, Thermi, Greece.
Emmanouil DermitzakisDepartment of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Maria HassapidouDepartment of Nutritional Sciences and Dietetics, International Hellenic University, Thermi, Greece.
Manolis K LinardakisDepartment of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece.
Anthony G KafatosDepartment of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece.
University of Crete · GRInternational Hellenic University · GRAristotle University of Thessaloniki · GRUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNutritional disorders cause secondary osteoporosis as well as musculoskeletal metabolism dysfunction. The Christian Orthodox Church's fasting in Mediterranean countries such Greece and Cyprus, or M.C.O.C. diet consists of self-restraint from food and/or food categories for 180 ± 19 days of total, especially of animal protein and dairy products. This case-control study attempts to investigate the effect of this fasting pattern on musculoskeletal metabolism and bone density.

designOne hundred fasters (or M.C.O.C. diet followers; 68 women and 32 men, mean 59 ± 6.5) with 32 years average fasting time and 100 non-fasters (66 females and 34 males, mean 58.1 ± 6.8; the control group of Mediterranean diet followers) over the age of 50, including menopausal women, were interviewed, as well as physically and laboratory examined along with DEXA measurements of the L2-4 vertebrae and hips. Nutrition data gathered through a 3-day food record during a non-fasting period, while energy intakes calculated on a daily food consumption basis.

resultsGiven the overall low incidence of osteoporosis in the Mediterranean diet, it appears to be more than three times higher than that of M.C.O.C. diet despite the periodic restriction of food intake of animal origin into a slightly hypothermic pattern, which in turn is characterized by increased consumption of multicolored vegetable foods.

conclusionsAbstinence from dairy products and meat does not adversely affect musculoskeletal metabolism or bone density. M.C.O.C. diet seems to be "healthy" eating habit for the musculoskeletal system, as future studies expected to confirm.

Indexed as

Diet, MediterraneanFastingAnimalsBone DensityCase-Control StudiesDietFemaleGreeceHumansMale

Identifiers

PMID32483221
OpenAlexW3031544083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.